Goathead (generic name)

treats Infertility, Coronary artery disease, and Exercise performance enhancement
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Safety

DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.

Allergies

Avoid in individuals with a known allergy or hypersensitivity to Tribulus terrestris or its constituents.

Side Effects and Warnings

Tribulus terrestris appears to be generally safe with a few adverse events of insomnia and menorrhagia (heavy menstrual bleeding) occurring. Use cautiously in patients with menstrual disorders. One case of pneumothorax (air between the lungs and the lining of the chest cavity) upon digestion of the fruit has been reported. In another case report, the patient developed a polyp in the lobar bronchus of the right interior lobe due to the presence a tribulus fruit spine. In a case report, gynecomastia (excessive development of male breasts) was observed in a weight-trainer taking an herbal supplement containing tribulus.

Most adverse effects reported, such as exceptionally strong libido, general excitation, and insomnia have been from use of the combination product Tribestan®. However, these adverse effects cannot be solely attributed to tribulus, due to the other ingredients in this product.

Although not well studied in humans, a saponin from tribulus may reduce levels of glucose and total cholesterol. Use cautiously in patients with diabetes (high blood sugar) or using hypoglycemic (blood sugar altering) medication, as tribulus may decrease blood sugar levels.

Although not well studied in humans, tribulus may increase prostate weight. Use cautiously in patients with benign prostatic hyperplasia (enlarged prostate) or prostate cancer.

Pregnancy and Breastfeeding

Tribulus is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence. Traditionally, tribulus has been used as an abortifacient (induces abortion).

Interactions

Interactions with Drugs

Tribulus may add to calcium channel blocker or beta-blocker effects due to its negative chronotropic activity in cardiac muscle.

Tribulus may exacerbate digoxin effects. Caution is advised.

Tribulus may exhibit diuretic effects (increases urine flow). Caution is advised when used with other drugs that have diuretic effects.

Tribulus may lower blood glucose levels. Caution is advised when using medications that may also lower blood sugar. Patients taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.

Tribulus has been found to have blood pressure lowering effects, and may affect patients taking drugs that also alter blood pressure.

Based on preliminary study and studies of combination products containing tribulus, tribulus may increase levels of steroid hormones.

Interactions with Herbs and Dietary Supplements

Tribulus may exacerbate the effects of cardiac glycoside herbs.

Tribulus may exhibit diuretic effects (increase urine flow). Caution is advised when used with other herbs that have diuretic effects.

Tribulus may lower blood glucose levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.

Tribulus has been found to have blood pressure lowering effects, and may affect patients taking herbs that also alter blood pressure.

Based on preliminary study and studies of combination products containing tribulus, tribulus may increase levels of steroid hormones.

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