This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Julie Conquer, PhD (RGB Consulting); Tracee Abrams, PharmD (University of Rhode Island); Nicole Giese, MS (Natural Standard Research Collaboration); Juliann Goodfriend, PharmD (Northeastern University); Toni Schaeffer, PhD, PharmD (Albany College of Pharmacy); Rebecca Strauss, PharmD (Northeastern University); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration); Mario M. Zeolla, PharmD, BCPS (Albany College of Pharmacy).
Azuma J, Sawamura A, Awata N, et al. Therapeutic effect of taurine in congestive heart failure: a double-blind crossover trial. Clin.Cardiol. 1985;8(5):276-282.
Balkan J, Oztezcan S, Hatipoglu A, et al. Effect of a taurine treatment on the regression of existing atherosclerotic lesions in rabbits fed on a high-cholesterol diet. Biosci Biotechnol Biochem 2004;68(5):1035-1039.
Colombo C, Battezzati PM, Podda M, et al. Ursodeoxycholic acid for liver disease associated with cystic fibrosis: a double-blind multicenter trial. The Italian Group for the Study of Ursodeoxycholic Acid in Cystic Fibrosis. Hepatology 1996;23(6):1484-1490.
Hagar HH, El Etter E, Arafa M. Taurine attenuates hypertension and renal dysfunction induced by cyclosporine A in rats. Clin Exp Pharmacol Physiol 2006;33(3):189-196.
Li Q, Guo JC, Jin HB, et al. Involvement of taurine in penicillin-induced epilepsy and anti-convulsion of acupuncture: a preliminary report. Acupunct Electrother Res 2005;30(1-2):1-14.
Mas MR, Isik AT, Yamanel L, et al. Antioxidant treatment with taurine ameliorates chronic pancreatitis in an experimental rat model. Pancreas 2006;33(1):77-81.
Merli M, Bertasi S, Servi R, et al. Effect of a medium dose of ursodeoxycholic acid with or without taurine supplementation on the nutritional status of patients with cystic fibrosis: a randomized, placebo-controlled, crossover trial. J.Pediatr.Gastroenterol.Nutr. 1994;19(2):198-203.
Oriyanhan W, Yamazaki K, Miwa S, et al. Taurine prevents myocardial ischemia/reperfusion-induced oxidative stress and apoptosis in prolonged hypothermic rat heart preservation. Heart Vessels 2005;20(6):278-285.
Rakotoambinina B, Marks L, Badran AM, et al. Taurine kinetics assessed using [1,2-13C2]taurine in healthy adult humans. Am.J.Physiol Endocrinol.Metab 2004;287(2):E255-E262.
Smith LJ, Lacaille F, Lepage G, et al. Taurine decreases fecal fatty acid and sterol excretion in cystic fibrosis. A randomized double-blind trial. Am.J.Dis.Child 1991;145(12):1401-1404.
Spencer AU, Yu S, Tracy TF, et al. Parenteral nutrition-associated cholestasis in neonates: multivariate analysis of the potential protective effect of taurine. JPEN J Parenter.Enteral Nutr 2005;29(5):337-343.
Spohr C, Brons C, Winther K, et al. No effect of taurine on platelet aggregation in men with a predisposition to type 2 diabetes mellitus. Platelets. 2005;16(5):301-305.
Tabassum H, Rehman H, Banerjee BD, et al. Attenuation of tamoxifen-induced hepatotoxicity by taurine in mice. Clin Chim.Acta 2006;370(1-2):129-136.
Tyson JE, Lasky R, Flood D, et al. Randomized trial of taurine supplementation for infants less than or equal to 1,300-gram birth weight: effect on auditory brainstem-evoked responses. Pediatrics 1989;83(3):406-415.
Zhang M, Bi LF, Fang JH, et al. Beneficial effects of taurine on serum lipids in overweight or obese non-diabetic subjects. Amino.Acids 2004;26(3):267-271.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.