Taurine is likely safe when taken by mouth by adults in doses up to 3 grams daily for up to one year.
Up to 9 grams per day has been studied, but there is currently no proven effective dose for any indication. Nonetheless, for congestive heart failure, 3-6 grams of taurine has been taken by mouth daily for up to one year. The same dose has been studied for up to two months for high blood pressure. For diabetes mellitus type 2, 1,000-1,500 milligrams daily in divided doses for 30-90 days has been used. For hypercholesterolemia, 6 grams of taurine powder daily for three weeks has been used. For iron-deficiency anemia, 1,000 milligrams of taurine per day has been used for 20 weeks, and for liver disease, 4 grams has been used three times daily for six weeks. For visual fatigue, 3 grams per day for twelve days has been used. As a vaccine adjuvant, 9 grams taurine on the same day and one day prior to influenza vaccine administration has been used. For obesity, 3 grams daily for seven weeks has been used.
Injections of taurine have been used in the treatment of epilepsy, and as a nutritional supplement or coronary bypass surgery. Injections should only be given under the supervision of a qualified healthcare professional.
Taurine is possibly safe in children when taken by mouth at 30 milligrams per kilogram body weight daily for up to four months.
Other doses have been studied, but are not necessarily safe or effective. For cystic fibrosis, 30-40 milligrams per kilogram body weight daily for seven days to six months has been used. As a fortified infant formula, 470 micromoles per liter of taurine has been taken by mouth for six days in pre-term and full term infants; 45 micromoles per liter taurine added to Similac Special Care® formula in low weight infants has also been taken by mouth until release from hospital or infant attained weight of 2,500 grams. As parenteral nutrition, 10.8 milligrams per kilogram per day during the first ten days of life has been used.