Artemisia annua (generic name)

treats Malaria and Cancer
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DISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Berger TG, Dieckmann D, Efferth T, et al. Artesunate in the treatment of metastatic uveal melanoma--first experiences. Oncol Rep. 2005;14(6):1599-1603.

Bertea CM, Freije JR, van der Woude H, et al. Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua. Planta Med 2005;71(1):40-47.

Chen HH, Zhou HJ, Wu GD, et al. Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1. Pharmacology 2004;71(1):1-9.

Efferth T. Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells. Curr Drug Targets. 2006;7(4):407-421.

Haynes RK. From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements. Curr Top Med Chem 2006;6(5):509-537.

Heide L. Artemisinin in traditional tea preparations of Artemisia annua. Trans R.Soc Trop.Med Hyg 2006;100(8):802.

Hsu E. The history of qing hao in the Chinese materia medica. Trans R.Soc Trop.Med Hyg 2006;100(6):505-508.

Lommen WJ, Schenk E, Bouwmeester HJ, et al. Trichome dynamics and artemisinin accumulation during development and senescence of Artemisia annua leaves. Planta Med 2006;72(4):336-345.

Mueller MS, Runyambo N, Wagner I, et al. Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria. Trans.R.Soc.Trop.Med Hyg. 2004;98(5):318-321.

Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop.Med Hyg. 2004;70(2):128-132.

Romero MR, Serrano MA, Vallejo M, et al. Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV). Planta Med 2006;72(13):1169-1174.

Singh NP, Lai HC. Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. Anticancer Res 2005;25(6B):4325-4331.

Van der Meersch H. [Review of the use of artemisinin and its derivatives in the treatment of malaria]. J Pharm Belg. 2005;60(1):23-29.

Wu GD, Zhou HJ, Wu XH. Apoptosis of human umbilical vein endothelial cells induced by artesunate. Vascul.Pharmacol. 2004;41(6):205-212.

Yance DR Jr., Sagar SM. Targeting angiogenesis with integrative cancer therapies. Integr.Cancer Ther. 2006;5(1):9-29.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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