Safflower (generic name)

treats Atherosclerosis, Diabetes mellitus type 2, Cardiovascular disorders, Total parenteral nutrition, Toxicity, Familial hyperlipidemia, Kidn...
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Attribution

This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Nicole Giese, MS (Natural Standard Research Collaboration); Tamara Milkin, PharmD (Northeastern University); Elizabeth Poole, PharmD (Drug Information Center, University of Missouri-Kansas City School of Pharmacy); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration).

Bibliography

DISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Axelrod L, Camuso J, Williams E, et al. Effects of a small quantity of omega-3 fatty acids on cardiovascular risk factors in NIDDM. A randomized, prospective, double-blind, controlled study. Diabetes Care 1994;17(1):37-44.

Burton-Freeman B, Davis PA, Schneeman BO. Interaction of fat availability and sex on postprandial satiety and cholecystokinin after mixed-food meals. Am J Clin Nutr 2004;80(5):1207-1214.

Clore JN, Stillman JS, Li J, et al. Differential effect of saturated and polyunsaturated fatty acids on hepatic glucose metabolism in humans. Am J Physiol Endocrinol.Metab 2004;287(2):E358-E365.

Dworatzek PD, Hegele RA, Wolever TM. Postprandial lipemia in subjects with the threonine 54 variant of the fatty acid-binding protein 2 gene is dependent on the type of fat ingested. Am J Clin Nutr 2004;79(6):1110-1117.

Eyjolfson V, Spriet LL, Dyck DJ. Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans. Med Sci Sports Exerc 2004;36(5):814-820.

Gradek WQ, Harris MT, Yahia N, et al. Polyunsaturated fatty acids acutely suppress antibodies to malondialdehyde-modified lipoproteins in patients with vascular disease. Am J Cardiol 4-1-2004;93(7):881-885.

Kaji K, Yoshida S, Nagata N, et al. An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C. J Gastroenterol. 2004;39(9):873-878.

Loo WT, Cheung MN, Chow LW. The inhibitory effect of a herbal formula comprising ginseng and carthamus tinctorius on breast cancer. Life Sci. 11-26-2004;76(2):191-200.

Nordstrom DC, Honkanen VE, Nasu Y, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Rheumatol.Int. 1995;14(6):231-234.

Park Y, Jones PG, Harris WS. Triacylglycerol-rich lipoprotein margination: a potential surrogate for whole-body lipoprotein lipase activity and effects of eicosapentaenoic and docosahexaenoic acids. Am J Clin Nutr 2004;80(1):45-50.

Radack K, Deck C, Huster G. The effects of low doses of n-3 fatty acid supplementation on blood pressure in hypertensive subjects. A randomized controlled trial. Arch Intern Med 1991;151(6):1173-1180.

Rallidis LS, Paschos G, Papaioannou ML, et al. The effect of diet enriched with alpha-linolenic acid on soluble cellular adhesion molecules in dyslipidaemic patients. Atherosclerosis 2004;174(1):127-132.

Simopoulos, AP. Omega-3 fatty acids and antioxidants in edible wild plants. Biol Res 2004;37(2):263-277.

Wilt TJ, Lofgren RP, Nichol KL, et al. Fish oil supplementation does not lower plasma cholesterol in men with hypercholesterolemia. Results of a randomized, placebo-controlled crossover study. Ann Intern Med 12-1-1989;111(11):900-905.

Zhang Q, Peng JH, Zhang XN. [A clinical study of Safflower Yellow injection in treating coronary heart disease angina pectoris with Xin-blood stagnation syndrome.]. Chin J Integr.Med 2005;11(3):222-225.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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