Phytolacca americana (generic name)

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This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration ( Idy Chu, PharmD (Massachusetts College of Pharmacy); Nicole Giese, MS (Natural Standard Research Collaboration); Sooyoun Kang, PharmD (Massachusetts College of Pharmacy); Lisa Scully, PharmD (Natural Standard Research Collaboration); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to Selected references are listed below.

Barkhordari A, Stoddart RW, McClure SF, McClure J. Lectin histochemistry of normal human lung. J Mol.Histol. 2004;35(2):147-156.

Cho SY, Sim JS, Kang SS, et al. Enhancement of heparin and heparin disaccharide absorption by the Phytolacca americana saponins. Arch Pharm Res 2003;26(12):1102-1108.

D'Cruz OJ, Uckun FM. Pokeweed antiviral protein: a potential nonspermicidal prophylactic antiviral agent. Fertil.Steril. 2001;75(1):106-114.

D'Cruz OJ, Waurzyniak B, Uckun FM. Mucosal toxicity studies of a gel formulation of native pokeweed antiviral protein. Toxicol.Pathol. 2004;32(2):212-221.

Erko B, Abebe F, Berhe N, et al. Control of Schistosoma mansoni by the soapberry Endod (Phytolacca dodecandra) in Wollo, northeastern Ethiopia: post-intervention prevalence. East Afr.Med J 2002;79(4):198-201.

Esser KB, Semagn K, Wolde-Yohannes L. Medicinal use and social status of the soap berry endod (Phytolacca dodecandra) in Ethiopia. J Ethnopharmacol. 2003;85(2-3):269-277.

Ndekha A, Hansen EH, Molgaard P, et al. Community participation as an interactive learning process: experiences from a schistosomiasis control project in Zimbabwe. Acta Trop. 2003;85(3):325-338.

Rajamohan F, Doumbia SO, Engstrom CR, et al. Expression of biologically active recombinant pokeweed antiviral protein in methylotrophic yeast Pichia pastoris. Protein Expr.Purif. 2000;18(2):193-201.

Rau E. Treatment of acute tonsillitis with a fixed-combination herbal preparation. Adv.Ther 2000;17(4):197-203.

Schlick J, Dulieu P, Desvoyes B, et al. Cytotoxic activity of a recombinant GnRH-PAP fusion toxin on human tumor cell lines. FEBS Lett. 4-28-2000;472(2-3):241-246.

Sussner U, Abel G, Schulte R, Kreis W. Isolation and characterisation of a cysteine protease (phytolacain G), from Phytolacca americana roots. Planta Med 2004;70(10):942-947.

Tadeg H, Mohammed E, Asres K, et al. Antimicrobial activities of some selected traditional Ethiopian medicinal plants used in the treatment of skin disorders. J Ethnopharmacol. 8-22-2005;100(1-2):168-175.

Treyvaud V, Marston A, Dyatmiko W, et al. Molluscicidal saponins from Phytolacca icosandra. Phytochemistry 2000;55(6):603-609.

Woldeamanuel Y, Abate G, Chryssanthou E. In vitro activity of Phytolacca dodecandra (Endod) against dermatophytes. Ethiop.Med J 2005;43(1):31-34.

Yang WH, Wieczorck M, Allen MC, et al. Cytotoxic activity of gonadotropin-releasing hormone (GnRH)-pokeweed antiviral protein conjugates in cell lines expressing GnRH receptors. Endocrinology 2003;144(4):1456-1463.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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