l-carnitine (generic name)

a nutraceutical product - treats Infertility, Arrhythmia, Exercise performance, Alzheimer's disease, Diabetic neuropathy, Peyronie's disease, C...
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This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Julie Conquer, PhD (RGB Consulting); Gary Ferguson, ND (Southcentral Foundation); Sayuri Fujita, PharmD (Massachusetts College of Pharmacy); Nicole Giese, MS (Natural Standard Research Collaboration); Mary Giles, PharmD (University of Rhode Island); Richard Liebowitz, MD (Duke University); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Ruslan Voloshin, PharmD (Massachusetts College of Pharmacy); Wendy Weissner, BA (Natural Standard Research Collaboration).


DISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Bazzato G, Coli U, Landini S, et al. Myasthenia-like syndrome after D,L- but not L-carnitine. Lancet 5-30-1981;1(8231):1209.

Bazzato G, Mezzina C, Ciman M, et al. Myasthenia-like syndrome associated with carnitine in patients on long- term haemodialysis. Lancet 5-12-1979;1(8124):1041-1042.

Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Metab 2001;86(8):3579-3594.

Bohmer T, Bergrem H, Eiklid K. Carnitine deficiency induced during intermittent haemodialysis for renal failure. Lancet 1-21-1978;1(8056):126-128.

Casciani CU, Caruso U, Cravotto E, et al. Effect of L-carnitine on lipid pattern in haemodialysis. Lancet 12-13-1980;2(8207):1309-1310.

El Beshlawy A, Abd El Raouf, Mostafa F, et al. Diastolic dysfunction and pulmonary hypertension in sickle cell anemia: is there a role for L-carnitine treatment? Acta Haematol. 2006;115(1-2):91-96.

Ellaway C, Williams K, Leonard H, et al. Rett syndrome: randomized controlled trial of L-carnitine. J Child Neurol 1999;14(3):162-167.

Holme E, Greter J, Jacobson CE, et al. Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Lancet 8-26-1989;2(8661):469-473.

Jirillo E, Altamura M, Munno I, et al. Effects of acetyl-L-carnitine oral administration on lymphocyte antibacterial activity and TNF-alpha levels in patients with active pulmonary tuberculosis. A randomized double blind versus placebo study. Immunopharmacol.Immunotoxicol. 1991;13(1-2):135-146.

Lacour B, Di Giulio S, Chanard J, et al. Carnitine improves lipid anomalies in haemodialysis patients. Lancet 10-11-1980;2(8198):763-764.

Maebashi M, Kawamura N, Sato M, et al. Lipid-lowering effect of carnitine in patients with type-IV hyperlipoproteinaemia. Lancet 10-14-1978;2(8094):805-807.

Persico G, Amato B, Aprea G, et al. The early effects of intravenous L-propionyl carnitine on ulcerative trophic lesions of the lower limbs in arteriopathic patients: a controlled randomized study. Drugs Exp Clin Res 1995;21(5):187-198.

Sima AA, Calvani M, Mehra M, et al. Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials. Diabetes Care 2005;28(1):89-94.

Singh RB, Niaz MA, Agarwal P, et al. A randomised, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction. Postgrad.Med J 1996;72(843):45-50.

Thomas S, Fischer FP, Mettang T, et al. Effects of L-carnitine on leukocyte function and viability in hemodialysis patients: A double-blind randomized trial. Am J Kidney Dis 1999;34(4):678-687.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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