gotu kola (generic name)

an herbal product - treats Diabetic microangiopathy, Anxiety, Cognitive function, Wound healing, Chronic venous insufficiency/varicose veins, a...
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This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ethan Basch, MD (Natural Standard Research Collaboration); Samuel Basch, MD (Mt. Sinai Medical Center); Heather Boon, PharmD (University of Toronto); J. Kathryn Bryan, BA Natural Standard Research Collaboration); Colleen Collins, PharmD (Massachusetts General Hospital); Nicole Giese, MS (Natural Standard Research Collaboration); Paul Hammerness, MD (Harvard Medical School); Sadaf Hashmi, MD, MPH (Natural Standard Research Collaboration); Kelly Dowhower Karpa, PhD, RPh (Pennsylvania State University); Beth Kerbel, PharmD (Northeastern University); Erica Seamon, PharmD (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Minney Varghese, BS (Northeastern University); Mamta Vora, PharmD (Northeastern University); Wendy Weissner, BA (Natural Standard Research Collaboration); Jen Woods, BS (Natural Standard Research Collaboration).

Bibliography

DISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Belcaro G, Laurora G, Cesarone MR, et al. Efficacy of Centellase (R) in the treatment of venous hypertension evaluated by a combined microcirculatory model. Curr Ther Res 1989;46(6):1015-1026.

Belcaro GV, Grimaldi R, Guidi G, et al. Treatment of diabetic micorangiopathy with TTFCA. A microcirculatory study with laser-Doppler flowmetry, P02/PC02, and capillary permeability measurements. Curr Ther Res 1990;47(3):421-428.

Belcaro GV, Rulo A, Grimaldi R. Capillary filtration and ankle edema in patients with venous hypertension treated with TTFCA. Angiology 1990;41(1):12-18.Belcaro GV, Grimaldi R, Guidi G. Improvement of capillary permeability in patients with venous hypertension after treatment with TTFCA. Angiology 1990;41(7):533-540.

Bradwejn J, Zhou Y, Koszycki D, et al. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20(6):680-684.

Carlson JJ, Farquhar JW, DiNucci E, et al. Safety and efficacy of a ginkgo biloba-containing dietary supplement on cognitive function, quality of life, and platelet function in healthy, cognitively intact older adults. J Am Diet.Assoc 2007;107(3):422-432.

Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52(10 suppl 2):S49-S54.

Cesarone MR, Incandela L, De Sanctis MT, et al. Flight microangiopathy in medium- to long-distance flights: prevention of edema and microcirculation alterations with total triterpenic fraction of Centella asiatica. Angiology 2001;52(10 suppl 2):S33-S37.

Cesarone MR, Belcaro G, De Sanctis MT, et al. Effects of the total triterpenic fraction of Centella asiatica in venous hypertensive microangiopathy: a prospective, placebo-controlled, randomized trial. Angiology 2001;52(10 suppl 2):S15-S18.

De Sanctis MT, Belcaro G, Incandela L, et al. Treatment of edema and increased capillary filtration in venous hypertension with total triterpenic fraction of Centella asiatica: A clinical, prospective, placebo-controlled, randomized, dose-ranging trial. Angiology 2001;52(10 suppl 2):S55-S59.

Incandela L, Belcaro G, De Sanctis MT, et al. Total triterpenic fraction of Centella asiatica in the treatment of venous hypertension: a clinical, prospective, randomized trial using a combined microcirculatory model. Angiology 2001;52(10 suppl 2):S61-S67.

Incandela L, Cesarone MR, Cacchio M, et al. Total triterpenic fraction of Centella asiatica in chronic venous insufficiency and in high-perfusion microangiopathy. Angiology 2001;52(10 suppl 2):S9-S13.

Incandela L, Belacaro G, Cesarone MR, et al. Treatment of diabetic microangiopathy and edema with total triterpenic fraction of Centella asiatica: a prospective, placebo-controlled randomized study. Angiology 2001;52(10 suppl 2):S27-S31.

Kaziulin AN, Petukhov AB, Kucheriavyi IuA. [Efficiency of includes of bioactive substances in diet of patient with hepatic encephalopathy]. Vopr.Pitan. 2006;75(2):40-44.

Ramanathan M, Sivakumar S, Anandvijayakumar PR, et al. Neuroprotective evaluation of standardized extract of Centella asciatica in monosodium glutamate treated rats. Indian J Exp Biol 2007;45(5):425-431.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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