gotu kola (generic name)

an herbal product - treats Diabetic microangiopathy, Anxiety, Cognitive function, Wound healing, Chronic venous insufficiency/varicose veins, a...
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Tradition

WARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Abscesses, airline flight-induced lower extremity edema, Alzheimer's disease, amenorrhea, anemia, antidepressant, anti-fertility agent, anti-infective, antioxidant, antivenom, aphrodisiac, asthma, bladder lesions, blood purifier, bronchitis, bruises, burns, cancer, cellulitis, cerebrovascular disease, cholera, colds, corneal abrasion, dehydration, diarrhea, diuretic, dysentery, eczema, elephantiasis, energy, epilepsy, eye diseases, fatigue, fever, fungal infections, gastric ulcers, gastric ulcer prophylaxis, gastritis, gonorrhea, hair growth promoter, hemorrhoids, hepatic disorders, hepatitis, herpes simplex virus-2, high blood pressure, hot flashes, immunomodulator, inflammation, influenza, jaundice, keloid formation prevention, leprosy, leukoderma, libido, longevity, malaria, memory enhancement, menstrual disorders, mental disorders, mood disorders, neuroprotection, pain, periodontal disease, peripheral vasodilator, physical exhaustion, psoriasis, radiation-induced behavioral changes, respiratory infections, restless leg syndrome, rheumatism, scabies, scar healing, scleroderma, shigellosis, shingles (post-herpetic neuralgia), skin diseases, skin graft donor wounds, snakebites, striae gravidarum (stretch marks), sunstroke, syphilis, systemic lupus erythematosus, tonsillitis, tuberculosis, urinary retention, urinary tract infection, vaginal discharge, vascular fragility, venous disorders.

Dosing

Adults (over 18 years old)

There is no proven effective dose for gotu kola in adults. For chronic venous insufficiency, varicose veins, or venous hypertension, various dosing regimens have been studied, including 60-120 milligrams daily Centellase® (TTFCA); 30 milligrams twice daily Centellase®; 30 milligrams three times daily TTFCA; 60mg twice daily TTFCA; 60 milligrams TTFCA three times daily. Preliminary studies suggest a dose-dependent response, with better results using 60 milligrams three times daily TTFCA. TECA (titrated extract from Centella asiatica) has also been studied, at a dose of 60-120 milligrams daily. For diabetic microangiopathy, 60 milligrams twice daily of TTFCA (total triterpenic fraction of Centella asiatica) has been studied. Combination products such as CognoBlend® have been studied for liver cirrhosis and cognitive enhancement.

Children (under 18 years old)

There is no proven effective dose for gotu kola in children.

Safety

DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.

Allergies

Avoid in individuals with a known allergy or hypersensitivity to gotu kola or any of its constituents, including asiaticoside, asiatic acid, or madecassic acid. There are numerous reports of allergic contact dermatitis after topical gotu kola use. Allergic contact dermatitis has been reported after the use of topical Blasteostimulina® cream, containing Centella asiatic extract, and after the application of topical Madecassol® ointment.

Side Effects and Warnings

Studies suggest that gotu kola has few side effects when taken by mouth. Reported symptoms include stomach upset and nausea. In animal research, large doses of gotu kola cause drowsiness, increase cholesterol levels, and raise blood sugar levels. Individuals with diabetes or high cholesterol should avoid gotu kola. Use caution if driving or operating heavy machinery while taking gotu kola as it may cause drowsiness. Asiaticoside, an ingredient of gotu kola, may have weak cancer-causing effects when applied to the skin. There is also a report of night eating syndrome associated with gotu kola.

Gotu kola is not related to the kola nut (Cola nitida, Cola acuminata). Gotu kola is not a stimulant and does not contain caffeine.

Pregnancy and Breastfeeding

In animal studies, gotu kola reduces the ability of a female to become pregnant, but it is not known if this effect occurs in humans. Gotu kola is not recommended during pregnancy or breast-feeding because there is little safety and efficacy information available.

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