treats Multiple myeloma and Hepatitis B
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Interactions with Drugs
Two toxic deaths, both attributable to neutropenia and sepsis, were reported in a phase II trial studying spirogermanium in combination with 5-fluorouracil. Significant toxicity has occurred and caution is advised.
Ge-132 (germanium sesquioxide) may enhance morphine analgesia in humans following both oral and intraperitoneal injection. Caution is advised.
Interactions with Herbs & Dietary Supplements
Insufficient available evidence.
This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Tracee Rae Abrams, PharmD (University of Rhode Island); Ethan Basch, M.Sc (Memorial-Sloan-Kettering Cancer Center); Heather Boon, BScPhm, PhD (University of Toronto); Mary Giles, PharmD (University of Rhode Island); Nicole Giese, MS (Natural Standard Research Collaboration); Dana A. Hackman, BS (Northeastern University); David Kiefer, MD (Bastyr University, University of Washington); Cathy DeFranco Kirkwood, MPH, CCCJS-MAC (MD Anderson Cancer Center); Lisa Scully, PharmD (Massachusetts College of Pharmacy); Kristopher Swinney, PharmD (Massachusetts College of Pharmacy - Worcester); Isabell Sylesky, PharmD (Northeastern University); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration); Shannon Welch, PharmD (Northeastern University).
BibliographyDISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
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Shamir M, Sprung CL. [Fatal multiple organ system dysfunction associated with germanium metal used in complementary therapy]. Harefuah 11-16-1997;133(10):446-7, 502.
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Tsutsumi Y, Tanaka J, Kanamori H, et al. Effectiveness of propagermanium treatment in multiple myeloma patients. Eur.J Haematol. 2004;73(6):397-401.
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.