Oplopanax horridus (generic name)
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This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Nicole Giese, MS (Boston University); Dana A. Hackman, BS (Northeastern University); David Kiefer, MD (University of Arizona); Cathy DeFranco Kirkwood MPH (CCCJS-MA, MD Anderson Cancer Center); Adam McLean, MPharm (University of Nottingham); Lisa Scully, PharmD (Massachusetts College of Pharmacy); Erica Seamon, PharmD (Nova Southeastern University), Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Bloxton JD. Notes on Economic Plants: Bioactive constituents of Alaskan devil's root (Oplopanx horridus, Araliaceae). Econ Bot. 2002;56(3):285-289.
Gruber JW, Kittipongpatana N, Bloxton JD, et al. High-performance liquid chromatography and thin-layer chromatography assays for Devil's Club (Oplopanax horridus). J Chromatogr Sci 2004;42(4):196-199.
Justice JW. Use of devil's club in Southeast Alaska. Alaska Med 1966;8(2):36-39.
Kobaisy M, Abramowski Z, Lermer L, et al. Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. J Nat Prod 1997;60(11):1210-1213.
Lantz T, Swerhun K, Turner N. Devil's club an ethnobotanical review. HerbalGram 2004;(62):33-48.
McCutcheon AR, Ellis SM, Hancock RE, et al. Antibiotic screening of medicinal plants of the British Columbian native peoples. J Ethnopharmacol 1992;37(3):213-223.
McCutcheon AR, Ellis SM, Hancock RE, et al. Antifungal screening of medicinal plants of British Columbian native peoples. J Ethnopharmacol 1994;44(3):157-169.
McCutcheon AR, Roberts TE, Gibbons E, et al. Antiviral screening of British Columbian medicinal plants. J Ethnopharmacol 1995;49(2):101-110.
Mi HM, Li CG, Su ZW, et al. [Studies on the chemical constituents and antifungal activities of essential oil from Oplopanax elatus nakai]. Yao Xue Xue Bao 1987;22(7):549-552.
Smith GW. Arctic pharmacognosia II. Devil's Club, Oplopanax horridus. J Ethnopharmacol 1983;7(3):313-320.
Stuhr ET, Henry FB. An investigation of the root bark of Fastia horrida. Pharm Archives 1944;(15):9-15.
Turner NJ. Traditional Use of Devil's-Club (Oplopanax horridus; Araliaceae) by Native Peoples in Western North America. J Ethnobiol 1982;2(1):17-38.
Wattenberg LW. Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene (nerolidol). Carcinogenesis 1991;12(1):151-152.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.