Coleus forskohlii (generic name)

treats Breathing aid for intubation, Cardiomyopathy, Glaucoma, Erectile dysfunction, Depression and schizophrenia, Asthma, Anti-inflammatory ac...
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Dosing

Adults (18 years and older)

There is no proven safe or effective dose for coleus. Many natural medicine experts recommend 50 milligrams of coleus extract (18% forskolin), taken 1-3 times daily by mouth, although the safety or efficacy of these doses has not been demonstrated. A dose of 250 milligrams of less-concentrated coleus extract (1% forskolin) taken 1-3 times daily has also been commonly used. As a dried root, 6-12 grams daily has been used, and as a fluid extract, 6-12 milliliters daily has been used.

Colforsin daropate 0.5-0.75mcg/kg-1/min-1 has been used for its anti-inflammatory action after cardiopulmonary bypass and to aid in airway resistance after tracheal intubation. Although coleus has been studied for depression, schizophrenia, cardiomyopathy and glaucoma, no commercially available products have been proven safe for these uses.

Children (younger than 18 years)

There is no proven safe or effective dose for coleus in children.

Safety

DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.

Allergies

Avoid in individuals with a known allergy or hypersensitivity to Coleus forskohlii and related species. Rash may occur in sensitive individuals.

Side Effects and Warnings

Coleus is generally regarded as safe, although long-term safety data are lacking. Inhalation of forskolin may cause sore throat, upper respiratory tract irritation, mild to moderate cough, tremor, or restlessness. Coleus eye drops may produce a milky covering over the eyes.

Coleus may lower blood sugar and stimulate the thyroid gland. Use cautiously in patients with thyroid disorders. Also use cautiously in diabetic patients. Colenol, a compound isolated from coleus, stimulates insulin release.

Theoretically, coleus may increase the risk of bleeding. Use cautiously in patients with a history of bleeding, hemostatic disorders or drug-related hemostatic problems. Discontinue use in patients at least two weeks prior to surgical or dental procedure, due to risk of bleeding. Avoid use in patients with active bleeding.

Use cautiously in patients with low blood pressure or those at risk for hypotension. Also use cautiously in patients with heart disease or asthma.

Avoid during pregnancy due to possibility of abortifacient (abortion inducing) effects.

Pregnancy and Breastfeeding

Coleus is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence. It is unknown if coleus is excreted in the breast milk.

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