Ammonia treated quinic acid (QAA), ancajsillo Ancajsillo, ancayacu, aublet, auri huasca, bejuco de agua, cat's claw inner bark extract, C-Med-100®, deixa paraguayo, gambir, garabato, garabato amarillo, garabato blanco, garbato casha, garbato colorado, garbato gavilán, garra gavilán, geissoschizine methyl ether, Gou-Teng, griffe du chat, hawk's claw, jijyuwamyúho, jipotatsa, Krallendorn, kugkuukjagki, life-giving vine of Peru, misho-mentis, mitraphylline, nature's aspirin, Nauclea oculeata, Nauclea tomentosa, Ourouparia guianensis, Ourouparia tomentosa, paotati-mösha, paraguaya, Peruvian cat's claw, pole catechu, popokainangra, quinic acid (QA), radix Uncariae tomentosae (Willd.), rangayo, Rubiaceae (family), samento, tambor hausca, tomcat's claw, torõn, tsachik, tua juncara, Uncaria guianensis, Uncaria tomentosa, uña de gato, uña de gato de altura, uña de gato del bajo, uña de gavilán, uña a huasca, Uncaria guianensis, Uncaria tomentosa, unganangi, unganangui, un huasca, UT extract, UTE, vegicaps.
There are 34 Unicaria species other than Uncaria tomentosa.
Originally found in Peru, the use of cat's claw (Uncaria tomentosa) has been said to date back to the Inca civilization, possibly as far back as 2,000 years. It has been used for birth control, as an anti-inflammatory, an immunostimulant, for cancer, and as an antiviral. The Peruvian Ashaninka priests considered cat's claw (Uncaria tomentosa) to have great powers and life-giving properties and therefore used it to ward off disease.
Multiple plant species are marketed under the name cat's claw, the most common being Uncaria tomentosa and Uncaria guianensis. Both are used to treat the same indications, although supposedly the former may be a more efficacious immunostimulant.
Cat's claw (Uncaria tomentosa) may be contaminated with other Uncaria species, including Uncaria rhynchophylla (used in Chinese herbal preparations under the name Gou-Teng), which purportedly may lower blood pressure, lower heart rate, or act as a neuroinhibitor. Reports exist of a potentially toxic Texan grown plant, Acacia gregii, being substituted for cat's claw in commercial preparations.
In Germany and Austria, cat's claw is a registered pharmaceutical and can only be dispensed with a prescription. Today, cat's claw is widely used and is one of the top herbal remedies sold in the United States despite a lack of high quality human evidence.
There is insufficient evidence to recommend cat's claw for allergic respiratory diseases at this time. Early studies have been conducted in Europe assessing the effects of cat's claw in patients with allergic respiratory diseases; a 10-year follow-up revealed that some patients experienced improvements.
Cat's claw may reduce inflammation, and this has led to research of cat's claw for conditions such as rheumatoid arthritis. Large, high quality human studies are needed comparing effects of cat's claw alone vs. placebo before a conclusion can be drawn.
Preliminary evidence suggests that cat's claw may slow tumor growth. However, this research is very early and has not identified specific types of cancer that may benefit; the results are not clear. More studies are needed before a firm recommendation can be made.
A few early studies suggest that cat's claw may boost the immune system, including in patients with HIV. However, results from different studies have not agreed with each other. Therefore, there is not enough information to make a firm recommendation for this use.
Knee pain from osteoarthritis:
Early research suggests that cat's claw may reduce pain from knee osteoarthritis. Further research is needed to confirm these results.
There is no proven effective dose for cat's claw. Capsules, extracts, tinctures, decoctions, and teas are commercially available. As a capsule, 20 milligrams to 25 grams have been used, often taken in divided does.
Cat's claw is also available in preparations for the skin, but no specific doses have been shown to be safe or effective.
The dosing and safety of cat's claw have not been studied thoroughly in children, and it is recommended that doses are discussed with the child's healthcare provider before starting therapy.
People with allergies to plants in the Rubiaceae family or any species of Uncaria may be more likely to have allergic reactions to cat's claw. A typical allergic reaction may be itching or severe rash. Allergic inflammation of the kidneys has been reported.
Few side effects have been reported from using cat's claw at recommended doses. Most side effects are believed to be rare, and some side effects are theoretical and have not been reported in humans. Examples of possible side effects include stomach discomfort, nausea, diarrhea, slow heartbeats or altered rhythm of heartbeats, kidney disease, acute kidney failure, neuropathy, decreases in estrogen or progesterone levels, and an increased risk of bleeding. Because cat's claw theoretically may increase the risk of bleeding, patients may need to stop taking cat's claw before some surgeries and this needs to be discussed with a qualified healthcare provider. Caution is advised in patients with bleeding disorders or taking drugs that may increase the risk of bleeding. Dosing adjustments may be necessary.
Some natural medicine experts discourage the use of cat's claw in people with conditions affecting the immune system, such as AIDS or HIV, some types of cancer, multiple sclerosis, tuberculosis, and rheumatologic diseases (rheumatoid arthritis, lupus, etc.). However, there are no specific studies or reports in this area, and the risks of cat's claw use in people with these conditions are not clear.
Many tinctures contain high levels of alcohol and should be avoided when driving or operating heavy machinery.
Cat's claw cannot be recommended during pregnancy or breastfeeding. Historically, cat's claw has been used to prevent pregnancy and to induce abortion. Women who are pregnant or wish to become pregnant should not take cat's claw. Many tinctures contain high levels of alcohol, and should be avoided during pregnancy.