locust bean gum (generic name)

treats Diarrhea in children, Gastroesophageal reflux disease, and Hypercholesterolemia
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Interactions

Interactions with Drugs

Carob may alter blood sugar levels. Caution is advised when using medications that may also affect blood sugar. Patients taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare provider. Medication adjustments may be necessary.

Carob bean gum may reduce hyperlipidemia (high cholesterol) in adults and LDL ("bad") cholesterol levels in children and adolescents with elevated plasma LDL cholesterol levels. Caution is advised in patients taking cholesterol-lowering agents due to additive effects.

Although not well studied in humans, carob bean gum polysaccharides may block a step in rubella virus replication subsequent to virus attachment, and may interact with antiviral agents. Consult with a qualified healthcare professional, including a pharmacist, before combining therapies.

Carob leaf extracts may act as chemopreventive agents. Caution is advised when taking with other drugs with similar effects.

Carob bean gum may decrease bowel transit time or increase fecal weight. It may also reduce the adherence of Escherichia coli on intestinal epithelial. Thus, it may interact with laxatives or other agents taken by mouth, and caution is advised.

In children and infants with acute diarrhea, carob bean juice or carob pod powder may reduce the symptoms of infectious diarrhea. Caution is advised when taking carob with other agents that have similar effects.

Interactions with Herbs and Dietary Supplements

Based on a laboratory study, carob may reduce the adherence of Escherichia coli on intestinal epithelial.

Carob may lower blood sugar levels. Caution is advised when using herbs or supplements that can also alter blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.

Carob bean gum may reduce hyperlipidemia (high cholesterol) in adults and LDL ("bad") cholesterol levels in children and adolescents with elevated plasma LDL cholesterol levels. Caution is advised in patients taking cholesterol-lowering herbs, such as red yeast rice, due to additive effects.

Carob bean gum polysaccharides may block a step in rubella virus replication subsequent to virus attachment. Caution is advised in patients taking herbs with antiviral effects, due to possible additive effects.

Carob leaf extracts may act as chemopreventive agents. Caution is advised when taking with other herbs with similar effects.

Although not well studied in humans, carob bean gum may reduce the absorption of zinc, iron, copper, chromium and cobalt. Carob bean gum may decrease bowel transit time or increase fecal weight, and caution is advised when using with laxative herbs, such as psyllium.

Attribution

This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Thomas Brendler (PlantaPhile); Nicole Giese, MS (Natural Standard Research Collaboration); Joerg Gruenwald, PhD (Phytopharm Research); David Lee, PharmD (Massachusetts College of Pharmacy); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration).

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