locust bean gum (generic name)

treats Diarrhea in children, Gastroesophageal reflux disease, and Hypercholesterolemia
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Safety

DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.

Allergies

Avoid in individuals with a known allergy or hypersensitivity to carob (Ceratonia siliqua), its constituents, or any plants in the Fabaceae family, including tamarind. Pollen from the carob tree has been reported as an important inhalant allergen. Asthma and rhinitis to carob bean flour have been reported. Explosive vomiting, urticaria (hives), and a rash have also been reported following allergy to an anti-regurgitation milk formula containing carob bean gum in an infant. Individuals allergic to peanuts may also have cross-sensitivity to raw carob pulp.

Side Effects and Warnings

There are no reports of serious adverse effects related to the consumption of carob. The consumption in designated therapeutic doses can be generally considered as safe, although side effects may include a feeling of fullness. Carob is likely safe when consumed in amounts usually found in foods; in the United States carob has generally recognized as safe (GRAS) status.

Carob is possibly unsafe when used uncontrolled and unreflected in infants with gastroesophageal reflux, in pregnant women, or in patients with anemia, diabetes, hyperlipidemia (high cholesterol), hypouricemia (low uric acid), known allergies to members of the Fabaceae family, peanuts, or other nuts, or who have experienced previous complications with powdered, bulk forming laxative drinks. Carobis is also possibly safe when used by patients taking herbs or drugs by mouth, as carob bean gum may decrease bowel transit time. Use cautiously in patients with diabetes as locust bean gum may decrease glucose response and glycemic index.

In patients with renal (kidney) failure, ingestion of locust bean gum showed laxative effects, decreased high blood pressure, and caused a fall in serum urea, creatinine, and phosphorus.

A five month-old child who was allergic to an anti-regurgitation milk formula containing carob bean gum experienced urticaria (hives) and a rash within 30 minutes of administration of the formula. Thickening milk feeds (Carobel®) may cause necrotizing enterocolitis (a serious intestinal illness in babies that may cause tissue damage to the intestines) in low birth-weight infants.

Avoid in patients with a chromium, cobalt, copper, iron, or zinc disorder or deficiency as carob bean gum may reduce absorption of these minerals. Use cautiously in patients with anemia (red blood cell deficiency) as carob bean gum may reduce the absorption of iron. Avoid in patients with metabolic disorders, with acute diarrhea or in underweight infants.

Pregnancy and Breastfeeding

Carob is not recommended in pregnant or breastfeeding women due to a lack of available scientific data.

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