What is trismus-pseudocamptodactyly syndrome?
Trismus-pseudocamptodactyly syndrome (TPS) is
a rare muscle disorder that affects the mouth, hands, and feet. The syndrome is
also known as Dutch-Kennedy syndrome and Hecht syndrome. Learn more about this
What are the symptoms of TPS?
The symptoms of TPS vary from one person to
another. It causes shortened muscles and tendons. The most common symptom is
limited mobility of the mouth, which can cause problems with chewing. Other symptoms
- limited motion of the arms or legs
- clenched fists
- a club foot
- abnormalities of the feet and hands
What causes TPS?
TPS is an inherited disease. A mutation of
the MYH8 gene causes TPS. It’s autosomal dominant. This means that a person can
inherit the abnormal gene from only one parent. The only known risk factor for
this condition is a family history of TPS.
How is TPS diagnosed?
A doctor can usually diagnose TPS at birth.
It requires a full physical examination. A doctor will also look at the
family’s medical history because TPS is an inherited syndrome. The signs of TPS
begin to show during infancy.
How is TPS treated?
No cure for TPS is available. However, you
can have surgery to alleviate some of the symptoms of TPS. Doctors also often
suggest physical and occupational therapy for people with TPS who have trouble
walking or who have dexterity issues.