Are Gastritis and Duodenitis?
Gastritis is inflammation of the stomach lining. Duodenitis is
inflammation of the duodenum (the first part of the small intestine), which is
located just below your stomach. Both gastritis and duodenitis have the same
causes and treatments.
Both conditions may occur in men and women of all ages. The
conditions may be acute or chronic. The acute forms come on suddenly and last
for a short time. The chronic forms may progress slowly and last for months or
years. The conditions are curable and generally don’t cause any long-term
Causes Gastritis and Duodenitis?
The most common cause of gastritis and duodenitis is a bacterium
called Helicobacter pylori (H. pylori). Large amounts of the
bacteria invading your stomach or small intestine can cause inflammation.
H. pylori can be transferred from person to person. It can also
be transmitted through contaminated food and water, although this is uncommon
in the United States. According to the National
Digestive Diseases Information Clearinghouse, approximately 20 to 50
percent of people in the United States may be infected with H. pylori. In comparison,
up to 80 percent of people in developing countries are infected with the
Other common causes of gastritis and duodenitis include the
long-term use of certain medications, such as aspirin, ibuprofen, or naproxen,
or drinking too much alcohol.
Less common causes include:
- Crohn’s disease (inflammation of the digestive
- an autoimmune condition (when the body makes
antibodies that attack the cells lining the stomach) resulting in atrophic
gastritis (destruction of stomach lining)
- bile reflux (when bile flows from the duodenum
into the stomach)
- having certain viral infections — such as herpes
simplex virus — along with a weak immune system
- traumatic injury to your stomach or small
- being placed on a breathing machine
- extreme stress caused by major surgery, severe
body trauma, shock
- ingesting caustic substances or poisons (strong
substances that can burn or corrode your tissues if you swallow them)
- excessive cigarette smoking
- radiation therapy for cancer
- chemotherapy for cancer
Duodenitis, and Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is the chronic inflammation of part
or all of the digestive tract. The exact cause is unknown, but doctors believe
that IBD may be the result of an immune disorder. It’s also possible that the
disease is inherited. Examples of IBD include ulcerative colitis (inflammation
of the colon and rectum) and Crohn’s disease. Crohn’s disease may affect any
part of the digestive tract and often spreads beyond the intestinal lining and
into other tissues.
A study published in Inflammatory
Bowel Diseases reported that people with inflammatory bowel disease
are much more likely to develop a form of gastritis or duodenitis that isn’t caused
by H. pylori than people who don’t have the disease.
Are the Symptoms of Gastritis and Duodenitis?
Gastritis and duodenitis don’t always produce signs or symptoms.
When they do, common symptoms include:
- burning or cramping feeling in the stomach
- feeling full shortly after you begin eating
In some cases, feces may appear black in color and vomit may look
like used coffee grounds. These symptoms can indicate internal bleeding. Call
your doctor right away if you experience either of these symptoms.
Are Gastritis and Duodenitis Diagnosed?
There are several tests your doctor can use to diagnose gastritis
and duodenitis. H. pylori can be detected through blood, stool, or
breath tests. For a breath test, you will be instructed to drink a clear,
tasteless liquid and then breathe into a bag. This will help your doctor detect
any extra carbon dioxide gas in your breath if you are infected with H. pylori.
Your doctor may also perform an upper endoscopy with biopsy. During
this procedure, a small camera attached to a long, thin, flexible tube (an
endoscope) is moved down the throat to look into the stomach or small intestine.
This test will allow your doctor check for inflammation. Your doctor may take a
few small tissue samples for further testing if any inflammation can’t be
Are Gastritis and Duodenitis Treated?
Depending on the cause of your condition, your symptoms may go
away without treatment. The type of care you receive will depend on the cause
and severity of your gastritis or duodenitis. Fastritis and duodenitis usually clear
up without complications.
H. pylori infections are treated with antibiotics. Your
doctor may recommend a combination of drugs to kill the infection, and most
people will need to take antibiotics for two weeks or longer.
Over-the-counter acid blockers (drugs that work to reduce the
amount of acid released into your digestive tract) may be recommended. These
- cimetidine (Tagamet)
- famotidine (Pepcid)
- ranitidine (Zantac)
Proton pump inhibitors (drugs that block cells that produce acid)
are also used to treat these conditions. These include:
- esomeprazole (Nexium)
- lansoprazole (Prevacid)
- omeprazole (Prilosec)
Your doctor may prescribe prescription-strength acid reducers to
keep stomach acid from irritating the lining of your digestive tract.
Your doctor may suggest antacids to neutralize stomach acid and
relieve pain. These are over-the-counter and don’t need to be prescribed.
Antacid options include:
- calcium carbonate (Tums)
- magnesium hydroxide (milk of magnesia)
calcium carbonate and magnesium
Antacids can prevent your body from absorbing other medications,
so it is recommended that you take antacids at least an hour before other
medications to avoid this side effect.
Avoid smoking, alcohol, spicy foods, acidic beverages (such as orange
juice or pineapple juice), and medications (such as aspirin) that are hard on
the stomach. All of these can make your symptoms worse.
Should You Call Your Doctor?
Make an appointment with your doctor if your symptoms don’t go
away with treatment. Call your doctor immediately if:
- you have a fever of 100.4ºF or higher
- your vomit looks like used coffee grounds
- your feces are black or tarry
- you have severe abdominal pain
Untreated cases of gastritis and duodenitis can become chronic.
This can lead to stomach ulcers and stomach bleeding. In rare cases, extensive
thinning of the stomach lining can change the cells over time and increase your
risk of developing stomach cancer.
Talk to your doctor if your gastritis or duodenitis isn’t
clearing up so you can determine the cause and make sure you get the treatment