Dementia is a general term for a decline in mental ability that affects your
everyday functioning. Common symptoms include:
- memory loss
- difficulty thinking
- difficulty communicating
- difficulty with coordination and motor functions
- general confusion and disorientation
Several factors can affect your risk for developing dementia. You can change
some of these factors, such as smoking, but not others, such as genetics.
It’s important to understand that a risk factor isn’t a cause. For example,
diabetes is a risk factor for both Alzheimer’s disease (AD) and vascular
dementia, but that doesn’t mean it causes AD or vascular dementia. Not all
people with diabetes develop dementia.
risk factors for dementia
Risk factors associated with dementia include the following:
Atherosclerosis is the thickening and hardening of artery walls due to plaque
buildup. Plaque is made of cholesterol, fat, calcium, and other substances in
the blood. This buildup can narrow your arteries and interfere with the flow of
blood to your brain. This impairs the ability of your brain cells to function
properly. This can ultimately lead to the death of these brain cells and their
connections to other brain cells.
A high level of LDL cholesterol increases your risk of developing vascular
dementia. This may be due to the association between atherosclerosis and high
This amino acid naturally circulates in your blood and is a building block
of protein. A high level of homocysteine is a risk factor for a number of
- Alzheimer’s disease
- vascular dementia
- cognitive impairment
Diabetes may be associated with an increased risk of developing both AD and
vascular dementia. Diabetes is also a risk factor for atherosclerosis and
stroke. Both of these can contribute to vascular dementia.
Psychological and experiential
Psychological and experiential factors may be a risk factor for dementia as
well. For example, if you tend to socially isolate yourself or don’t regularly
engage in cognitively stimulating activities, you may be at an increased risk
of developing AD.
Mild cognitive impairment
MCI can be thought of as a stage between normal forgetfulness and dementia.
However, if you have MCI, it doesn’t mean you’ll develop Alzheimer’s. But most
cases of Alzheimer’s start with MCI. Symptoms for MCI include:
- memory loss greater than expected
for your age
- memory deficiency is great enough to be
noticed and measured
- continued independence because the deficiency
isn’t enough to compromise your ability to care of yourself and conduct normal
By middle age, most people with Down syndrome have the plaques and tangles
of Alzheimer’s disease. Many also develop dementia.
and lifestyle risk factors for dementia
The risk of developing Alzheimer’s disease, vascular dementia, and several
other dementias increases as you age. In the United States, one in nine people
over the age of 65 has Alzheimer’s, about five million people, according to the
Alzheimer’s Association. One in three
seniors dies with Alzheimer’s or another form of dementia.
Many forms of dementia have a genetic component and it often runs in
families. In addition, certain mutations in specific genes have been identified
as increasing the risk for developing dementia.
A study in the JAMA Neurology journal found that smoking may
significantly increase your risk of mental decline and dementia. If you smoke,
you have a higher risk of atherosclerosis and other types of vascular disease. These
diseases may contribute to the increased risk of dementia.
Drinking large amounts of alcohol also increases your risk of developing a
type of dementia known as Korsakoff syndrome. Symptoms of Korsakoff syndrome
- difficulty learning new information
- short-term memory loss
- long-term memory gaps
Many risk factors are involved in developing dementia, including medical
conditions, lifestyle choices, genetics, and old age. If you have a high risk
for developing dementia, see your doctor about how you can prevent it and any
lifestyle changes that may help.