tadalafil (generic name)

Adcirca (brand name)

It is used to treat pulmonary arterial hypertension
(tah DA la fil)
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What is this medicine?

TADALAFIL (tah DA la fil) is used to treat pulmonary arterial hypertension. This is a serious heart and lung condition. This medicine helps to improve symptoms and quality of life.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa
  • heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems
  • high or low blood pressure
  • kidney disease
  • liver disease
  • pulmonary veno-occlusive disease (PVOD)
  • stomach ulcers
  • stroke
  • an unusual or allergic reaction to tadalafil, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. Take your medicine at regular intervals. Take both tablets at the same time, one after the other. Do not split your dose throughout the day. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin

This medicine may also interact with the following medications:

  • certain drugs for high blood pressure
  • certain drugs for the treatment of HIV infection or AIDS
  • certain drugs used for fungal or yeast infections, like fluconazole, itraconazole, ketoconazole, and voriconazole
  • certain drugs used for seizures like carbamazepine, phenytoin, and phenobarbital
  • grapefruit juice
  • macrolide antibiotics like clarithromycin, erythromycin, troleandomycin
  • medicines for prostate problems
  • rifabutin, rifampin or rifapentine

What should I watch for while using this medicine?

Do not change the dose of your medicine without asking your doctor. Call your doctor if your medication is not working for you. This may be a sign that your condition has become worse.

If you notice any changes in your vision while taking this drug, call your doctor or health care professional as soon as possible. Stop using this medicine and call your health care provider right away if you have a loss of sight in one or both eyes.

For males, contact you doctor or health care professional right away if an erection lasts longer than 4 hours or if it becomes painful. This may be a sign of serious problem and must be treated right away to prevent permanent damage.

If you experience symptoms of nausea, dizziness, chest pain, or arm pain after taking this medicine, you should discuss the episode with your doctor or health care professional as soon as possible.

Do not drink more than 4 alcohol-containing drinks in a short period of time when taking this medicine. When taken in excess, alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate or lowering your blood pressure.

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Last Updated: December 16, 2009
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