sildenafil (generic name)

Revatio (brand name)

It is used to treat pulmonary arterial hypertension
(sil DEN a fil)
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What is this medicine?

SILDENAFIL (sil DEN a fil) is used to treat pulmonary arterial hypertension. This is a serious heart and lung condition. This medicine helps to improve symptoms and quality of life.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

-anatomical deformation of the penis, Peyronie's disease, or history of priapism (painful and prolonged erection)
-bleeding disorders
-eye disease, vision problems
-heart disease
-high or low blood pressure
-history of blood diseases, like sickle cell anemia or leukemia
-kidney disease
-liver disease
-pulmonary veno-occlusive disease (PVOD)
-stomach ulcer
-an unusual or allergic reaction to sildenafil, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your doses at regular intervals about 4 to 6 hours apart. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

-cisapride
-cobicistat; elvitegravir; emtricitabine; tenofovir
-methscopolamine nitrate
-nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin
-nitroprusside
-other sildenafil products (Viagra)
-telaprevir
This medicine may also interact with the following medications:

-antiviral medicines for HIV or AIDS
-bosentan
-certain medicines for benign prostatic hyperplasia (BPH)
-certain medicines for blood pressure
-certain medicines for fungal infections like ketoconazole and itraconazole
-cimetidine
-erythromcyin

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Tell your doctor or health care professional right away if you have any change in your eyesight or hearing.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcoholic drinks; they can make you more dizzy.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-changes in vision
-chest pain
-decreased hearing
-fast, irregular heartbeat
-men: prolonged or painful erection (lasting more than 4 hours)
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-facial flushing
-headache
-nosebleed
-trouble sleeping
-upset stomach

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: September 06, 2012
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