sevelamer (generic name)

Renvela (brand name)

It binds phosphates in the stomach and prevents them from being absorbed into the body
(se VEL a mer)
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What is this medicine?

SEVELAMER (se VEL a mer) is a polymer. It binds phosphates in the stomach and prevents them from being absorbed into the body. This medicine is used in patients with chronic kidney disease on dialysis to prevent dangerous increases in phosphates.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bowel obstruction
  • difficulty swallowing
  • stomach surgery or disorder
  • an unusual or allergic reaction to sevelamer, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Take with meals. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Empty the entire contents of each packet into a cup and mix thoroughly with water. If you are using the 0.8 g packet, mix with 1 ounce (30 milliliters) of water. One ounce is equivalent to either 6 teaspoons or 2 tablespoons of water. If you are using the 2.4 g packet, mix with 2 ounces (60 milliliters) of water. Two ounces is equivalent to 4 tablespoons of water. Multiple packets can be mixed together with the right amount of water. The powder does not dissolve in water. Stir the mixture vigorously just before drinking. Drink entire mixture within 30 minutes.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • phosphorus containing product or supplement

This medicine may also interact with the following medications:

  • ciprofloxacin
  • medicines for an irregular heartbeat
  • medicines for seizure control
  • medicines for thyroid disorder

What should I watch for while using this medicine?

Visit your doctor or healthcare professional for regular check ups. Follow the diet as directed by your doctor.

If you are taking other medications, take them at least 1 hour before or 3 hours after taking this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • new or worsening constipation
  • stomach pain
  • vomiting

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • diarrhea
  • stomach upset, nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: October 14, 2009
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