insulin isophane and insulin regular (generic name)

This medicine lowers the amount of sugar in your blood
(REG yuh ler IN su lin; ISO fane IN su lin)
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What is this medicine?

REGULAR INSULIN: ISOPHANE INSULIN (REG yuh ler IN su lin; ISO fane IN su lin) is a human-made form of insulin. This medicine lowers the amount of sugar in your blood. It is a combination insulin that starts working about 30 minutes after it is injected and works for as long as 12 to 24 hours.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • episodes of hypoglycemia
  • kidney disease
  • liver disease
  • an unusual or allergic reaction to insulin, metacresol, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection under the skin. Use exactly as directed. It is important to follow the directions given to you by your doctor or health care professional. Your doctor or health care professional will tell you how long to wait after you inject your dose before eating a meal. Most of the time, you should wait about 30 minutes. You will be taught how to use this medicine and how to adjust doses for activities and illness. Do not use more insulin than prescribed. Do not use more or less often than prescribed.

Always check the appearance of your insulin before using it. This medicine should be white and cloudy before mixing and uniformly cloudy after mixing. To mix, roll the vial gently 10 times in your hands. Do not use it if it is colored, if it has solid particles in it, or if it does not mix.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What if I miss a dose?

It is important not to miss a dose. Your health care professional or doctor should discuss a plan for missed doses with you. If you do miss a dose, follow their plan. Do not take double doses.

What may interact with this medicine?

  • other medicines for diabetes

Many medications may cause an increase or decrease in blood sugar, these include:

  • alcohol containing beverages
  • aspirin and aspirin-like drugs
  • chloramphenicol
  • chromium
  • diuretics
  • female hormones, like estrogens or progestins and birth control pills
  • heart medicines
  • isoniazid
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • male hormones or anabolic steroids
  • medicines for weight loss
  • medicines for allergies, asthma, cold, or cough
  • medicines for mental problems
  • niacin
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • pentamidine
  • phenytoin
  • probenecid
  • quinolone antibiotics like ciprofloxacin, levofloxacin, ofloxacin
  • some herbal dietary supplements
  • steroid medicines like prednisone or cortisone
  • thyroid medicine

Some medications can hide the warning symptoms of low blood sugar. You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:

  • beta-blockers such as atenolol, metoprolol, propranolol
  • clonidine
  • guanethidine
  • reserpine

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Last Updated: April 07, 2011
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