nizatidine (generic name)

Axid (brand name)

It is used to treat stomach or intestinal ulcers
(ni ZA ti deen)
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What is this medicine?

NIZATIDINE (ni ZA ti deen) is a type of antihistamine that blocks the release of stomach acid. It is used to treat stomach or intestinal ulcers. It can relieve ulcer pain and discomfort, and the heartburn from acid reflux.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • kidney or liver disease
  • pain or difficulty swallowing
  • an unusual or allergic reaction to nizatidine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Follow the directions on the prescription label. If you only take this medicine once a day take it at bedtime. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • aspirin and aspirin-like medicines
  • delavirdine
  • itraconazole
  • ketoconazole

What should I watch for while using this medicine?

Tell your doctor or health care professional if your ulcer pain does not start to get better or gets worse. You may need to take this medicine for several days before your symptoms get better.

Do not take with aspirin, ibuprofen, or other antiinflammatory medicines unless directed to do so by your health care professional. These can make your condition worse.

Do not smoke cigarettes or drink alcohol. These increase irritation in your stomach and can increase the time it will take for your ulcer to heal.

If you get black, tarry stools or vomit up what looks like coffee grounds, call your doctor or health care professional right away. You may have a bleeding ulcer.

If you need to take an antacid you should take it at least 1 hour before or 1 hour after this medicine. This medicine will not work as well if taken at the same time as an antacid.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • agitation, nervousness
  • breast swelling and tenderness, or sexual difficulties (impotence) in men
  • confusion or hallucinations
  • dark yellow or brown urine
  • skin rash, itching
  • yellowing of the skin or eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • diarrhea
  • dizziness
  • headache

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: July 13, 2009
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