metoclopramide (generic name)

Reglan (brand name)

It is used to treat the symptoms of gastroesophageal reflux disease (GERD) like heartburn
(met oh kloe PRA mide)
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What is this medicine?

METOCLOPRAMIDE (met oh kloe PRA mide) is used to treat the symptoms of gastroesophageal reflux disease (GERD) like heartburn. It is also used to relieve the symptoms of slow stomach emptying in people with diabetes.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • breast cancer
  • depression or other mental illness
  • diabetes
  • heart failure or heart rhythm problems
  • high blood pressure
  • if you often drink alcohol
  • kidney disease
  • liver disease
  • Parkinson's disease or a movement disorder
  • pheochromocytoma
  • seizures
  • stomach obstruction, bleeding, or perforation
  • an unusual or allergic reaction to metoclopramide, sulfites, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Take this medicine at least 30 minutes before eating and at bedtime. Leave the tablet in the sealed blister pack until you are ready to take it. With dry hands, open the blister and gently remove the tablet. If the tablet breaks or crumbles, throw it away and take a new tablet out of the blister pack. Place the tablet in the mouth and allow it to dissolve, and then swallow. You do not need water to take this medicine. Do not take your medicine more often than directed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • acetaminophen
  • cyclosporine
  • digoxin
  • medicines for blood pressure
  • medicines for diabetes, including insulin
  • medicines for hay fever and other allergies
  • medicines for depression, especially an Monoamine Oxidase Inhibitor (MAOI)
  • medicines for Parkinson's disease, like levodopa
  • medicines for sleep or for pain
  • tetracycline

What should I watch for while using this medicine?

It may take a few weeks for your condition to improve. Do not take this medicine for longer than 12 weeks. The longer you take this medicine and the more that you take, the more likely you are to have side effects. If you are an older patient, a female, or you have diabetes, you may be at increased risk for side effects. Contact your health care professional right away if you have movements that you cannot control such as lip smacking, rapid movements of the tongue, unusual movements of the eyes, head, or arms.

Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.

Do not treat yourself for high fever. Ask your health care professional for advice.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcoholic drinks.

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Last Updated: November 12, 2009
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