diltiazem (generic name)

Cardizem (brand name)

It affects the amount of calcium found in your heart and muscle cells
(dil TYE a zem)
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What is this medicine?

DILTIAZEM (dil TYE a zem) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • heart disease, low blood pressure, irregular heartbeat
  • liver disease
  • previous heart attack
  • an unusual or allergic reaction to diltiazem, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection or infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following:
  • cisapride
  • hawthorn
  • pimozide
  • ranolazine
  • red yeast rice

This medicine may also interact with the following medications:

  • carbamazepine
  • cimetidine
  • cyclosporine
  • digoxin
  • local anesthetics or general anesthetics
  • medicines for high blood pressure or heart problems

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • confusion, mental depression
  • feeling faint or lightheaded, falls
  • pinpoint red spots on the skin
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • slow, irregular heartbeat
  • swelling of the ankles, feet
  • unusual bleeding or bruising

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • change in sex drive or performance
  • constipation or diarrhea
  • flushing of the face
  • headache
  • nausea, vomiting
  • tired or weak
  • trouble sleeping

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: April 09, 2009
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