pyridoxine (generic name)
- Auto Immune Conditions
- Bladder & Kidney Health
- Brain & Nervous System
- Care Transitions
- Dental Health
- Emotional Health
- Eye Health
- Falls Prevention
- Financial Planning
- General Safety
- Health Care Basics
- Healthy Living
- Hearing Loss
- Heart Health
- High Blood Pressure
- Life Transitions
- Lung Health
- Men's Health
- Nutrition & Weight Management
- Pain Management
- Preventive Health
- Sexual Health
- Stomach & Digestive Health
- Stress & Anxiety
- Women's Health
TraditionWARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Acne, alcohol intoxication, allergies, appetite stimulation, arthritis, cancer prevention, chorea, conjunctivitis (pinkeye), cystitis, diabetic neuropathy, diuresis (increased urine production), dizziness, Down's syndrome, high cholesterol, improving dream recall, infertility, menopausal symptoms, migraine headaches, motion sickness, muscle cramps, night leg cramps, poisoning (mushroom), psychosis, radiation sickness, sickle cell anemia, skin conditions.
Adults (over 18 years old)
Recommended Dietary Allowances (RDAs) of vitamin B6: Males (19-50 years) 1.3 milligrams; males (51 years and older) 1.7 milligrams; females (19-50 years) 1.3 milligrams; females (51 years and older) 1.5 milligrams. Some researchers think the RDA for women 19-50 years should be increased to 1.5-1.7 milligrams per day. Pregnant women, 1.9 milligrams; and lactating women, 2 milligrams.
Recommended maximum daily intake of vitamin B6: Adults, pregnant, and lactating women (over 18 years) 100 milligrams. A doctor and pharmacist should be consulted for dosing in other conditions.
Children (under 18 years old)
Recommended Dietary Allowances (RDAs) of vitamin B6: Infants (0-6 months) 0.1 milligrams; infants (7-12 months) 0.3 milligrams; children (1-3 years) 0.5 milligrams; children (4-8 years) 0.6 milligrams; children (9-13 years) 1 milligram; males (14-18 years) 1 milligram per day; females (14-18 years) 1.2 milligrams per day.
Recommended maximum daily intake of vitamin B6: Children (1-3 years) 30 milligrams; (4-8 years) 40 milligrams; children (9-13 years) 60 milligrams. Males, females, pregnant, and lactating females (14-18 years) 80 milligrams.
SafetyDISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.
Patients should avoid vitamin B6 products if they are sensitive or allergic to any of their ingredients.
Side Effects and Warnings
Some individuals seem to be particularly sensitive to vitamin B6 and may have problems at lower doses. Overall, pyridoxine is generally considered safe in adults and children when used appropriately at recommended doses. Avoid excessive dosing.
Acne, skin reactions, allergic reactions, and photosensitivity have been reported.
Nausea, vomiting, abdominal pain, loss of appetite, and increased liver function test results (serum aspartate transaminase (AST, SGOT)) have been reported.
Headache, paresthesia, somnolence, and sensory neuropathy have been reported.
Breast soreness or enlargement, decreased serum folic acid levels, seizures after large doses, hypotonia, and respiratory distress in infants have also been reported.
Pregnancy and Breastfeeding
Vitamin B6 is likely safe when used orally in doses not exceeding the recommended dietary allowance (RDA). Vitamin B6 is possibly safe when used orally and appropriately in amounts exceeding the recommended dietary allowance. A special sustained-release multi-ingredient product is U.S. Food and Drug Administration (FDA)-approved for use in pregnancy. However, it should not be used long-term or without medical supervision and close monitoring or in more excessive doses. There is some concern that high-dose maternal pyridoxine can cause neonatal seizures.
Vitamin B6 is likely safe when used orally in doses not exceeding the Recommended Dietary Allowance (RDA). There is insufficient reliable information about the safety of pyridoxine when used in higher doses in lactating women. Because most breastfeeding women do not consume the RDA of vitamin B6 in their normal diets and do not provide totally breastfed infants with the RDA of this vitamin, higher doses of vitamin B6 may be recommended although benefits have not been well proven.