Artemisia (generic name)

treats Malaria and Cancer
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Safety

DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.

Allergies

Avoid in individuals with a known allergy or hypersensitivity to sweet annie or members of the Asteraceae/Compositae family such as dandelion, goldenrod, ragweed, sunflower, and daisy.

Side Effects and Warnings

Certain constituents in sweet annie (artemisinin and artesunate) have been well-tolerated when taken by mouth with no reported adverse effects. However, there is a lack of available information on the safety of sweet annie and caution is advised.

Use cautiously in patients with compromised heart or brain function, as a related species has shown potential toxicity.

Use cautiously in patients who are pregnant or recovering from surgery or other wounds.

Use cautiously in patients with compromised immune function, as sweet annie may have immunosuppressive activity.

Pregnancy & Breastfeeding

Sweet annie is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence. Sweet annie may inhibit angiogenesis, which is the development of new blood vessels.

Interactions

Interactions with Drugs

Sweet annie may inhibit angiogenesis, which is the development of new blood vessels. Caution is advised in patients taking agents that affect angiogenesis.

Although not well studied in humans, sweet annie may also inhibit bacterial and fungal growth. Thus, patients taking antibiotics and antifungals should be aware that additive effects might occur.

Artesunate, a constituent found in sweet annie, may be incompatible with quinolines, which are used as food preservatives and in making antiseptics. These should not be confused with quinolones, which are a family of broad-spectrum antibiotics.

Sweet annie has been studied for its antimalarial and anticancer effects and use with other antimalarial or anticancer agents may have additive effects.

Sweet annie may have antioxidant and immunosuppressive activity. Consult with a qualified healthcare professional, including a pharmacist, to check for possible interactions.

Interactions with Herbs & Dietary Supplements

Sweet annie may inhibit angiogenesis, which is the development of new blood vessels. Caution is advised in patients taking herbs or supplements that affect angiogenesis.

Although not well studied in humans, sweet annie may also inhibit bacterial and fungal growth. Thus, patients taking antibiotics and antifungals should be aware that additive effects might occur.

Sweet annie has been studied for its antimalarial and anticancer effects and use with other antimalarial or anticancer herbs or supplements may have additive effects.

Sweet annie may have antioxidant and immunosuppressive activity. Consult with a qualified healthcare professional, including a pharmacist, to check for possible interactions with herbs or supplements with these effects.

Attribution

This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Dawn Costa, BA, BS (Natural Standard Research Collaboration); Nicole Giese, MS (Natural Standard Research Collaboration); Julie Goodfriend, PharmD (Northeastern University); Jamie Hegarty, PharmD (Massachusetts College of Pharmacy); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).

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