Rutin (generic name)

treats Varicose veins, Venous hypertension, Retinal vein occlusion, Edema, Thrombosis, Skin conditions, Schizophrenia, Microangiopathy, Retinop...
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Tradition

WARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Anticoagulant (dicoumarin damage), antioxidant, arrhythmia (cardiac rhythm abnormalities), atherosclerosis (arterial insufficiency), blood circulation (hemodynamic effects), brain injuries (cerebral function disorders), breast disease (mastopathy), common cold, coronary heart disease (CHD), deafness (sudden), dental procedures, eye diseases (euthyroid endocrine ophthalmopathy), gastric ulcer, Grave's disease (orbitopathy), immunomodulation, inflammation (oral, radiogenic sialadenitis and mucositis), mucositis, multiple sclerosis, musculoskeletal conditions (orthopedics), neck pain (cervical syndrome), nutritional deficiencies (trophic complications), osteoarthritis, pain, platelet aggregation (inhibition), post-operative pain, recovery after surgery (recovery from hemorrhoidectomy), sepsis, surgical uses, trauma.

Dosing

Adults (18 years and older):

There are various preparations of rutin used in clinical trials, including capsules, sachets and injections. Various dosages of hydroxyethylrutosides (HR) have been used, including 500 milligrams twice per day and 250-300 milligrams three to four times per day for 28 days. The most commonly used dose by mouth is 1-2 grams of rutin per day in divided doses for four weeks. However, up to 3,500 milligrams has been studied in clinical trials. Rutin has also been taken as trihydroxyethylrutosides (troxerutin) and oxerutin. Brand name products studied include Venoruton® and Paroven®.

Venoruton® 1 gram three times daily is a commonly used dose in combination with elastic compression for eight weeks to treat superficial vein thrombosis or flight edema.

Troxerutin is typically taken in higher doses of 3,500-7,000 milligrams per day in divided doses for up to four months. To treat venous insufficiency in premenstrual and pregnant women, 4 grams daily troxerutin has been given for four months.

One 300-milligram tablet of trihydroxyethylrutosides twice daily for up to four weeks has been used for hemorrhoids. However, 500-4,000 milligrams HR given by mouth twice daily in the treatment of first-, second-, or third-degree hemorrhoids is more commonly used.

For schizophrenia, 3 grams per day of a mixture of O-[beta-hydroxyethyl]-rutosides (Paroven®/Venoruton®) for three months has been used.

A single injection of 1,000 milligrams HR followed by 500 milligrams three times per day by mouth for four weeks has been used for chronic venous insufficiency. Injections should only be given under the supervision of a qualified healthcare professional, including a pharmacist.

Children (younger than 18 years):

There is no proven safe or effective dose of rutin in children.

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