psyllium (generic name)
a laxative - treats Obesity, Diarrhea, Colonoscopy preparation, Anal fissures, Fat excretion in stool, Colon cancer, Irritable bowel syndrome, ...
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BibliographyDISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Anderson JW, Allgood LD, Turner J, et al. Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia. Am J Clin Nutr 1999;70(4):466-473.
Barroso Aranda J, Contreras F, Bagchi D, et al. Efficacy of a novel chitosan formulation on fecal fat excretion: a double-blind, crossover, placebo-controlled study. J Med 2002;33(1-4):209-225.
Davidson MH, Dugan LD, Burns JH, et al. A psyllium-enriched cereal for the treatment of hypercholesterolemia in children: a controlled, double-blind, crossover study. Am J Clin Nutr 1996;63(1):96-102.
Davidson MH, Maki KC, Kong JC, et al. Long-term effects of consuming foods containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia. Am J Clin Nutr 1998;67(3):367-376.
Dennison BA, Levine DM. Randomized, double-blind, placebo-controlled, two-period crossover clinical trial of psyllium fiber in children with hypercholesterolemia. J Pediatr 1993;123(1):24-29.
Fernandez-Banares F, Hinojosa J, Sanchez-Lombrana JL, et al. Randomized clinical trial of Plantago ovata seeds (dietary fiber) as compared with mesalamine in maintaining remission in ulcerative colitis. Spanish Group for the Study of Crohn's Disease and Ulcerative Colitis (GETECCU). Am J Gastroenterol 1999;94(2):427-433.
Food and Drug Administration, HHS. Laxative drug products for over-the-counter human use; psyllium ingredients in granular dosage forms. Final rule. Fed Regist 2007 Mar 29;72(60):14669-74.
Jenkins DJ, Kendall CW, Vuksan V, et al. Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial. Am J Clin Nutr 2002;75(5):834-839.
Juarranz M, Calle-Puron ME, Gonzalez-Navarro A, et al. Physical exercise, use of Plantago ovata and aspirin, and reduced risk of colon cancer. Eur J Cancer Prev 2002;11(5):465-472.
MacMahon M, Carless J. Ispaghula husk in the treatment of hypercholesterolaemia: a double- blind controlled study. J Cardiovasc Risk 1998;5(3):167-172.
McRorie JW, Daggy BP, Morel JG, et al. Psyllium is superior to docusate sodium for treatment of chronic constipation. Aliment Pharmacol Ther 1998;12(5):491-497.
Murai M, Tamayama Y, Nishibe S. Phenylethanoids in the herb of Plantago lanceolata and inhibitory effect on arachidonic acid-induced mouse ear edema. Planta Med 1995 Oct;61(5):479-80.
Reid R, Fodor G, Lydon-Hassen K, et al. Dietary counselling for dyslipidemia in primary care: results of a randomized trial. Can J Diet Pract Res 2002;63(4):169-175.
Sierra M, Garcia JJ, Fernandez N, et al. Therapeutic effects of psyllium in type 2 diabetic patients. Eur J Clin Nutr 2002;56(9):830-842.
van Rosendaal GM, Shaffer EA, Edwards AL, et al. Issues raised by psyllium meta-analysis. Am J Clin Nutr 2001;73(3):653-654.