Liver Extract (generic name)
treats Hepatic disorders, Surgical uses, Chronic fatigue syndrome, Chronic hepatitis, and Pernicious anemia
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TraditionWARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Allergies, anemia, antioxidant, antiviral, blood clots, cardiovascular disease, celiac disease, corneal abrasions/ulcers, deficiency (vitamin B12), detoxification, drug addiction, enhanced muscle mass/strength, gastric acid secretion stimulation, hematopoiesis (stimulation of blood cell production), hepatoprotection, herpes simplex virus type 1, influenza virus infection, malabsorption (familial selective B12), methylmalonic aciduria, multiple sclerosis, obstetric and gynecological disorders, physical endurance, poisoning, renal failure (uremia), rheumatoid arthritis, stamina enhancer, tonic, tuberculosis, wound healing.
Adults (18 years and older):
There is no proven safe or effective dose for liver extract. A dose that has been used is 500 milligrams of liver extract 1-3 times per day. As an injection, 2 milliliters of liver extract has been administered daily for up to five days, although injections should only be given under the supervision of a qualified healthcare professional, including a pharmacist.
Children (younger than 18 years):
There is no proven safe or effective dose for liver extract in children, and use is not recommended.
SafetyDISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.
Avoid in individuals with a known allergy or hypersensitivity to liver extract or its constituents. Liver extract therapy has caused severe anaphylactic shock. Symptoms of sensitivity may include itching, slight flushing, tachycardia, cough, nasal and ocular discharges, and localized to generalized urticaria ("hives"), weakness, faintness, nausea, vomiting, bronchospasm, asthmatic reaction, substernal pain, collapse, rigor, profound shock, and rarely, death.
Side Effects and Warnings
Few adverse effects have been reported for liver extract, including anaphylactic shock and blood clotting changes. However, raw liver may contain liver flukes or the bacterium Vibrio fetus. The U. S. Food and Drug Administration (FDA) cautions against the consumption of any dietary supplement made from animal glands or organs, especially from cows and sheep from countries with known cases of bovine spongiform encephalitis (BSE, or "mad cow" disease) or scrapie. It is thought that these extracts may contain viable prions that could infect humans. It is not clear how the processing of liver extract affects the transmission of these organisms. Currently, there are no available reports of transmission of BSE through liver extract.
Other possible adverse effects of liver extract may include itching, slight flushing, tachycardia (fast heart rate), cough, nasal and ocular (eye) discharges, urticaria ("hives"), weakness, faintness, nausea, vomiting, bronchospasm, asthmatic reaction, substernal pain, collapse, rigor, profound shock, and rarely, death.
Use cautiously in patients taking antacids or with acid reflux as liver extract may increase gastric acid or pepsin output. Also use cautiously in patients with compromised immune function as liver extract may inhibit lymphocyte proliferation. Use cautiously in hepatopathic patients with reduced human growth hormone metabolic clearance rate, as liver extract may tend to normalize its metabolism.
Use cautiously in patients with clotting disorders as liver extract may stimulate production of red blood cells, affect blood clotting, or improve hemoglobin concentration in patients with impaired hepatic function.
Avoid liver extract in patients with iron metabolism disorders or iron shortage disorders, such as hemochromatosis (a metabolic disorder that causes increased absorption of iron).
Pregnancy and Breastfeeding
Liver extract is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence. Raw liver may be a possible source of Vibrio fetus septicemia in humans, although there are no available reports of liver extract causing Vibrio fetus septicemia.