lavender (generic name)
an herbal product - treats Improved workplace efficiency, Rheumatoid arthritis pain, Depression, Anxiety, Ear pain, Spasmolytic, Aggressive beh...
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Interactions with Drugs
Animal studies suggest that lavender used as aromatherapy or by mouth may increase the amount of drowsiness caused by some drugs. Examples include benzodiazepines such as lorazepam (Ativan®) or diazepam (Valium®), barbiturates such as phenobarbital, narcotics such as codeine, some antidepressants, and alcohol. Drowsiness caused by some seizure medicines may also be increased. Caution is advised while driving or operating machinery.
In theory, lavender may add to the effects of cholesterol-lowering drugs.
Lavender may have additive effects when used with prescription antidepressant medications, such as the tricyclic antidepressant imipramine.
Lavender may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants ("blood thinners") such as warfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).
Interactions with Herbs and Dietary Supplements
Lavender used as aromatherapy or by mouth may increase the amount of drowsiness caused by some herbs or supplements, such as valerian. Caution is advised while driving or operating machinery.
Lavender may interact with herbs and supplements taken for depression; use cautiously.
Lavender may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.
This information is based on a professional level monograph edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ethan Basch, MD (Memorial Sloan-Kettering Cancer Center); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Ivo Foppa, MD, PhD (Harvard University); Jenna Hollenstein, MS, RD (Natural Standard Research Collaboration); Eileen Kingsbury, PharmD (University of Rhode Island); Richard Liebowitz, MD (Duke University); Jamie Nelson, PharmD (University of Rhode Island); Michael Smith, MRPharmS, ND (Canadian College of Naturopathic Medicine); David Sollars, MAC, HMC (New England School of Acupuncture); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Nancy Tannous, PharmD (Northeastern University); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Akhondzadeh S, Kashani L, Fotouhi A, et al. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 2003;27(1):123-127.
Anderson C, Lis-Balchin M, Kirk-Smith M. Evaluation of massage with essential oils on childhood atopic eczema. Phytother Res 2000;14(6):452-456.
Basch E, Foppa I, Liebowitz R, et al. Lavender (Lavandula angustifolia Miller). J Herb Pharmacother 2004;4(2):63-78.
D'Auria FD, Tecca M, Strippoli V, et al. Antifungal activity of Lavandula angustifolia essential oil against Candida albicans yeast and mycelial form. Med Mycol 2005 Aug;43(5):391-6.
Dale A, Cornwell S. The role of lavender oil in relieving perineal discomfort following childbirth: a blind randomized clinical trial. J Adv Nurs 1994;19(1):89-96.
Graham PH, Browne L, Cox H, et al. Inhalation aromatherapy during radiotherapy: results of a placebo-controlled double-blind randomized trial. J Clin Oncol 6-15-2003;21(12):2372-2376.
Holmes C, Hopkins V, Hensford C, et al. Lavender oil as a treatment for agitated behaviour in severe dementia: a placebo controlled study. Int J Geriatr Psychiatry 2002;17(4):305-308.
Lewith GT, Godfrey AD, Prescott P. A single-blinded, randomized pilot study evaluating the aroma of Lavandula augustifolia as a treatment for mild insomnia. J Altern Complement Med 2005 Aug;11(4):631-7.
Moss M, Cook J, Wesnes K, et al. Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults. Int J Neurosci 2003;113(1):15-38.
Prashar A, Locke IC, Evans CS. Cytotoxicity of lavender oil and its major components to human skin cells. Cell Prolif 2004;37(3):221-229.
Rho KH, Han SH, Kim KS, et al. Effects of aromatherapy massage on anxiety and self-esteem in korean elderly women: a pilot study Int J Neurosci 2006 Dec;116(12):1447-55.
Snow LA, Hovanec L, Brandt J. A controlled trial of aromatherapy for agitation in nursing home patients with dementia. J Altern.Complement Med 2004;10(3):431-437.
Soden K, Vincent K, Craske S, et al. A randomized controlled trial of aromatherapy massage in a hospice setting. Palliat Med 2004;18(2):87-92.
Yip YB, Tse SH. An experimental study on the effectiveness of acupressure with aromatic lavender essential oil for sub-acute, non-specific neck pain in Hong Kong. Complement Ther Clin Pract. 2006 Feb;12(1):18-26.
Yip YB, Tse SH. The effectiveness of relaxation acupoint stimulation and acupressure with aromatic lavender essential oil for non-specific low back pain in Hong Kong: a randomised controlled trial. Complement Ther Med 2004;12(1):28-37.