Jiaogulan (Gynostemma pentaphyllum) is best known as a traditional Chinese medicine herb. In the Guizhou Province, it is used as an anti-aging herb and many people who drink jiaogulan tea reach very old age. However, no link between jiaogulan tea and living many years has been scientifically proven.
Jioagulan has shown some promise for treating cancer. Jiaogulan may also reduce nonalcoholic fatty liver disease, although more studies are needed in both of these areas before a recommendation can be made.
Preliminary evidence indicates that gypenosides extracted from Gynostemma pentaphyllum decrease cancer cell viability, arrest the cell cycle, and induce apoptosis (cell death) in human cancer cells. Immune function in cancer patients has also been studied. Additional study is needed in this area.
Fatty liver (nonalcoholic):
Gynostemma pentaphyllum extract may be helpful for those with nonalcoholic fatty liver disease when combined with other treatment. More research is needed in this area.
There is no proven effective dose for jiaogulan, although 80 milliliters of Gynostemma pentaphyllum extraction has been taken for four months in conjunction with a controlled diet for fatty liver.
There is no proven safe or effective dose for jiaogulan in children.
Avoid in individuals with a known allergy or hypersensitivity to jiaogulan (Gynostemma pentaphyllum) or its constituents.
Currently, there is not enough available evidence about the side effects of jiaogulan. Nonetheless, use cautiously in patients with hematologic (blood) conditions or taking anticoagulants or anti-platelet agents (blood thinners). Also, use cautiously in patients with diabetes as Gynostemma pentaphyllum may decrease insulin levels and insulin index scores.
Jiaogulan is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.