Hedera helix (generic name)

treats Asthma and Chronic obstructive pulmonary disease
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Interactions

Interactions with Drugs

Although not well studied in humans, English ivy may have antimutagenic (anticancer) properties. Caution is advised when combining English ivy with other anticancer agents.

English ivy may have antioxidant activity. Although not well studied in humans, combined use of English ivy and antioxidants may have additive effects.

Interactions with Herbs and Dietary Supplements

Although not well studied in humans, English ivy may have antimutagenic (anticancer) properties. Caution is advised when combining English ivy with other anticancer herbs or supplements.

English ivy may have antioxidant activity. Although not well studied in humans, combined use of English ivy and other herbs or supplements with antioxidants may have additive effects.

Attribution

This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): J. Kathryn Bryan, BA (Natural Standard Research Collaboration); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Nicole Giese, MS (Natural Standard Research Collaboration); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).

Bibliography

DISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Amara-Mokrane YA, Lehucher-Michel MP, Balansard G, et al. Protective effects of alpha-hederin, chlorophyllin and ascorbic acid towards the induction of micronuclei by doxorubicin in cultured human lymphocytes. Mutagenesis 1996;11(2):161-167.

Billington T, Pharmawati M, Gehring CA. Isolation and immunoaffinity purification of biologically active plant natriuretic peptide. Biochem Biophys Res Commun. 6-27-1997;235(3):722-725.

Gaillard Y, Blaise P, Darre A, et al. An unusual case of death: suffocation caused by leaves of common ivy (Hedera helix). Detection of hederacoside C, alpha-hederin, and hederagenin by LC-EI/MS-MS. J Anal Toxicol 2003;27(4):257-262.

Garcia M, Fernandez E, Navarro JA, et al. Allergic contact dermatitis from Hedera helix L. Contact Dermatitis 1995;33(2):133-134.

Gulcin I, Mshvildadze V, Gepdiremen A, et al. Antioxidant activity of saponins isolated from ivy: alpha-hederin, hederasaponin-C, hederacolchiside-E and hederacolchiside-F. Planta Med 2004;70(6):561-563.

Guo R, Pittler MH, Ernst E. Herbal medicines for the treatment of COPD: a systematic review. Eur Respir.J 2006;28(2):330-338.

Hofmann D, Hecker M, Volp A. Efficacy of dry extract of ivy leaves in children with bronchial asthma--a review of randomized controlled trials. Phytomedicine 2003;10(2-3):213-220.

Johnke H, Bjarnason B. [Contact dermatitis allergy to common ivy (Hedera helix L.)]. Ugeskr Laeger 6-20-1994;156(25):3778-3779.

Jors E. [The prevalence of skin and mucosal symptoms in gardeners handling Ficus benjamina (weeping fig) and Hedera helix (ivy). A cross-sectional study]. Ugeskr.Laeger 9-8-2003;165(37):3526-3529.

Massmanian A, Valcuende Cavero F, Ramirez Bosca A, et al. Contact dermatitis from variegated ivy (Hedera helix subsp. canariensis Willd.). Contact Dermatitis 1988;18(4):247-248.

Oka K, Saito F, Yasuhara T, et al. The allergens of Dendropanax trifidus Makino and Fatsia japonica Decne. et Planch. and evaluation of cross-reactions with other plants of the Araliaceae family. Contact Dermatitis 1999;40(4):209-213.

Ozdemir C, Schneider LA, Hinrichs R, et al. [Allergic contact dermatitis to common ivy (Hedera helix L.)]. Hautarzt 2003;54(10):966-969.

Taylor P. Healthy household hints. STEP Perspect 1999;99(3):16.

Villani P, Orsiere T, Sari-Minodier I, et al. [In vitro study of the antimutagenic activity of alphahederin]. Ann Biol Clin (Paris) 2001;59(3):285-289.

Yesudian PD, Franks A. Contact dermatitis from Hedera helix in a husband and wife. Contact Dermatitis 2002;46(2):125-126.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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