devil's claw (generic name)

an herbal product - treats Degenerative joint disease/osteoarthritis, Appetite stimulant, Digestive tonic, Low back pain, and Cancer
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Interactions

Interactions with Drugs

Devil's claw may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. A qualified healthcare provider should monitor patients taking drugs for diabetes by mouth or insulin closely. Medication adjustments may be necessary.

In theory, devil's claw may have an additive effect if taken with drugs used for pain, inflammation, high cholesterol, and gout. Drugs used for malaria may also interact.

Devil's claw may increase stomach acidity and therefore may affect drugs used to decrease the amount of acid in the stomach, such as antacids, sucralfate, ranitidine (Zantac®), and esomeprazole (Nexium®). Individuals taking any of these drugs should consult a qualified healthcare professional, including a pharmacist, before taking devil's claw.

Because devil's claw may affect heart rhythm, heart rate, and the force of heartbeats, individuals taking prescription drugs such as antiarrhythmics or digoxin (Lanoxin®) should consult their healthcare providers before taking devil's claw.

In theory, devil's claw may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants ("blood thinners") such as warfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).

Interactions with Herbs and Dietary Supplements

In theory, devil's claw may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.

In theory, devil's claw may interfere with other herbs and dietary supplements that affect heart rhythm, heart rate, and the force of heartbeats. Notably, bufalin/Chan Suis is a Chinese herbal formula that has been reported as toxic or fatal when taken with cardiac glycosides.

Devil's claw may add to the effects of herbs and dietary supplements that are used for pain or inflammation. Devil's claw may also interact with herbs or supplements used to treat malaria.

Devil's claw may reduce cholesterol concentrations and may add to the lipid-lowering effects of fish oil or garlic.

In theory, devil's claw may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.

Attribution

This information is based on a systematic review of scientific literature, and has been edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Ethan Basch, MD (Memorial Sloan-Kettering Cancer Center); Thomas Brendler (PlantaPhile); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Nicole Giese, MS (Natural Standard Research Collaboration); Joerg Gruenwald, PhD (Phytopharm Research); Kerri MacWhorter, PharmD (University of Rhode Island); Adrianne Rogers, MD (Boston Medical Center); Erica Seamon, PharmD (Natural Standard Research Collaboration); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Jen Woods, BS (Natural Standard Research Collaboration).

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