Aconitum (generic name)

treats Arrhythmia, Heart failure, and Post-operative pain
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Interactions

Interactions with Drugs

Anti-arrhythmic medications may antagonize the effects of aconite and increase the risk of cardiotoxicity or other side effects. Patients taking anti-arrhythmics or other heart medication should consult with a qualified healthcare professional, including a pharmacist.

Aconitine may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. Patients taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare provider. Medication adjustments may be necessary.

Aconitine may lower blood pressure. Caution is advised when using medications that may also lower blood pressure. Also, combined use of aconitine (an alkaloid found in aconite) with anesthetic medications or diuretic medications (those that increase urine flow) may also lower blood pressure. Caution is advised.

Theoretically, digoxin may interfere with aconitine effects on the heart. Combined use of these medications could be extremely dangerous and result in additive effects of both agents. Consult with a qualified healthcare professional, including a pharmacist.

Interactions with Herbs and Dietary Supplements

Aconitine may lower blood pressure. Caution is advised when using herbs or supplements that may also lower blood pressure. Also, combined use of aconitine (an alkaloid found in aconite) with herbs and supplements that have anesthetic effects or diuretic effects (those that increase urine flow) may also lower blood pressure. Caution is advised.

Aconitine may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar.

Theoretically, digoxin-like herbs or supplements (foxglove, Siberian ginseng) may interfere with aconite effects on the heart producing an unknown and potentially dangerous effect. Consult with a qualified healthcare professional, including a pharmacist before combining therapies.

Attribution

This information was created based on a systematic review of the scientific literature, and was peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Tracee Abrams, PharmD (University of Rhode Island); Chi Dam, PharmD (Northeastern University); Cynthia Dacey, PharmD (Natural Standard Research Collaboration); Chi Dam (Northeastern University); Nicole Giese, MS (Natural Standard Research Collaboration); Erica Rusie, PharmD (Nova Southeastern University); Elizabeth Sheehan, PharmD (Northeastern University); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration); Lisa Wendt, PharmD (Albany College of Pharmacy); Jen Woods, BA (Northeastern University).

Bibliography

DISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.

Alibeu JP, Jobert J. [Aconite in homeopathic relief of post-operative pain and agitation in children]. Pediatrie 1990;45(7-8):465-466.

Bao YX, Yu GR, Xu JM, et al. Effect of acute higenamine administration on bradyarrhythmias and HIS bundle. A clinical study of 14 cases and animal experiment on dogs. Chin Med J (Engl.) 1982;95(10):781-784.

Ernst E. Cardiovascular adverse effects of herbal medicines: a systematic review of the recent literature. Can J Cardiol 2003;19(7):818-827.

Imazio M, Belli R, Pomari F, Cecchi E, et al. Malignant ventricular arrhythmias due to Aconitum napellus seeds. Circulation 12-5-2000;102(23):2907-2908.

Lin CC, Chan TY, Deng JF. Clinical features and management of herb-induced aconitine poisoning. Ann Emerg Med 2004;43(5):574-579.

Lowe L, Matteucci MJ, Schneir AB. Herbal aconite tea and refractory ventricular tachycardia. N Engl J Med 10-6-2005;353(14):1532.

Oberbaum M, Schreiber R, Rosenthal, C, et al. Homeopathic treatment in emergency medicine: a case series. Homeopathy 2003;92(1):44-47.

Smith SW, Shah RR, Hunt JL, et al. Bidirectional ventricular tachycardia resulting from herbal aconite poisoning. Ann Emerg Med 2005;45(1):100-101.

Tai YT, But PP, Young K, et al. Cardiotoxicity after accidental herb-induced aconite poisoning. Lancet 11-21-1992;340(8830):1254-1256.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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