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Throat Cancer
Throat cancer refers to cancer of the voice box, the vocal cords, and other parts of the throat, such as the tonsils and the oropharynx.

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What is throat cancer?

Cancer is a class of diseases in which abnormal cells multiply and divide uncontrollably in the body. These abnormal cells form malignant growths called tumors. Throat cancer refers to cancer of the voice box, the vocal cords, and other parts of the throat, such as the tonsils and the oropharynx.

Throat cancer is often grouped into two categories: pharyngeal cancer and laryngeal cancer. Pharyngeal cancer forms in the pharynx (the hollow tube that runs from behind your nose to the top of your windpipe). Laryngeal cancer forms in the larynx (your voice box).

Throat cancer is relatively uncommon when compared to other cancers. The National Cancer Institute estimates 1.1 percent of adults will be diagnosed with pharyngeal cancer within their lifetime. An estimated 0.4 percent of men and women will be diagnosed with laryngeal cancer within their lifetime.

Recognizing potential signs of throat cancer

It can be difficult to detect throat cancer in its early stages. Common signs and symptoms of throat cancer include:

  • a change in your voice
  • trouble swallowing (dysphagia)
  • weight loss
  • sore throat
  • constant need to clear your throat
  • persistent cough (may cough up blood)
  • swollen lymph nodes in the neck
  • wheezing
  • ear pain
  • hoarseness

Make a doctor’s appointment if you experience any of these symptoms and they do not improve for a duration exceeding two to three weeks.

Causes and risk factors for throat cancer

Men are more likely to develop throat cancer than women. Certain lifestyle habits increase the risk of developing cancer of the throat. These include:

  • smoking
  • excessive alcohol consumption
  • vitamin A deficiency
  • exposure to asbestos
  • poor dental hygiene

There is also a connection between throat cancer and certain types of human papillomavirus infections (HPV). This is a sexually transmitted virus. The Cancer Treatment Centers of America say HPV infection is a risk factor for both cervical cancers in women and throat cancer.

Throat cancer has also been linked to other types of cancers. In fact, some people diagnosed with throat cancer are diagnosed with esophageal, lung, or bladder cancer at the same time. This is typically because cancers often have the same risk factors, or because cancer that begins in one part of the body can spread throughout the body in time.

Diagnosing throat cancer

At your appointment, your doctor will ask about your symptoms and medical history. If you’ve been experiencing symptoms such as a sore throat, hoarseness, and persistent cough with no improvement and no other explanation, they may suspect throat cancer.

To check for throat cancer, your doctor will perform a laryngoscopy or will refer you to a specialist who is trained to do these procedures. This procedure gives your doctor a closer view of your throat.

After you’re given a local anesthetic, your doctor inserts a long flexible tube down your throat, and uses a light and a mirror to examine your throat. If this test reveals abnormalities, your doctor may take a tissue sample from your throat (biopsy) and test the sample for cancer.

Staging throat cancer

If your doctor finds cancerous cells in your throat, they will order additional tests to identify the stage, or the extent, of your cancer.

  • Stage 0: The tumor has not invaded tissue beyond your throat.
  • Stage 1: The tumor is less than 7 cm and limited to your throat.
  • Stage 2: The tumor is slightly larger than 7 cm, but still limited to your throat.
  • Stage 3: The tumor has grown and has spread to nearby tissues and organs.
  • Stage 4: The tumor has spread to your lymph nodes and/or distant organs.

Your doctor can use a variety of tests to stage your throat cancer. Imaging tests like a CT scan or an MRI will allow your doctor to take a closer look at the chest, neck and head, giving them a better picture of the disease’s progression.

Treatment options for throat cancer

There are different treatment options for throat cancer. The treatment method recommended by your doctor will depend on the extent of your disease, among other factors.

Surgery

If the tumor in your throat is small, your doctor may surgically remove the tumor. This surgery would be done in the hospital while you are under sedation.

Radiation therapy

Following the removal of the tumor, your doctor may recommend radiation therapy. Radiation therapy uses high-energy rays to destroy malignant cancer cells. It would target any cancerous cells left behind by the tumor.

Chemotherapy

In the case of large tumors and tumors that have spread to the lymph nodes and other organs or tissue, your doctor may recommend radiation, as well as chemotherapy. Chemotherapy is a drug that kills and slows the growth of malignant cells.

Long-term outlook for throat cancer

If diagnosed early, throat cancer has a high cure rate.

Throat cancer may not be curable once malignant cells spread to parts of the body beyond the neck and head. However, people can continue treatment to prolong their life and slow the progression of the disease.

Some people with throat cancer require therapy after treatment to relearn how to swallow and speak. This can be improved upon by working with a speech therapist and a physical therapist. In addition, some people with throat cancer experience complications. These may include:

  • difficulty swallowing
  • disfigurement of the neck or face
  • inability to speak
  • difficulty breathing
  • skin hardening around the neck
Written by: Valencia Higuera
Edited by:
Medically Reviewed by: [Ljava.lang.Object;@61cd7344
Published: Jul 3, 2012
Published By: Healthline Networks, Inc.
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