voriconazole (generic name)

It stops the growth of some fungus and yeast
(vohr ih KON uh zohl)
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What is this medicine?

VORICONAZOLE (vohr ih KON uh zohl) is an antifungal. It stops the growth of some fungus and yeast. This medicine is used to treat many kinds of fungal infections.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • history of irregular heartbeat
  • kidney disease
  • liver disease
  • an unusual or allergic reaction to voriconazole, other antifungal medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Shake well before using. Use the oral dispenser that was supplied with this medicine to take your dose. Take this medicine on an empty stomach, at least one hour before or one hour after a meal. Do not take with food. Do not mix the dose with other drinks, flavorings, or medicines before taking. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think your are better. Do not skip doses or stop your medicine early.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • barbiturates like phenobarbital
  • carbamazepine
  • certain medicines for cholesterol like atorvastatin, lovastatin, and simvastatin
  • cisapride
  • efavirenz
  • ergotamine, dihydroergotamine
  • pimozide
  • quinidine
  • ranolazine
  • rifabutin
  • rifampin, rifapentine
  • ritonavir
  • sirolimus
  • red yeast rice

This medicine may also interact with the following medications:

  • alcohol
  • antiviral medicines for HIV or AIDS
  • cyclosporine
  • female hormones, like estrogens or progestins and birth control pills
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for diabetes
  • medicines for erectile dysfunction
  • medicines for heart disease like diltiazem, nicardipine
  • medicines for sleep
  • medicines that treat or prevent blood clots like warfarin
  • methadone
  • phenytoin
  • omeprazole
  • tacrolimus

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checkups. If you are taking this medicine for a long time you may need blood work. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Some fungal infections need many weeks or months of treatment to cure.

You may have changes in vision, including blurring and/or light sensitivity. Do not drive at night while taking this medicine. If you notice a change in vision avoid potentially hazardous tasks, such as driving or operating machinery. Avoid strong, direct sunlight during this therapy.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

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Last Updated: November 28, 2012
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