ticlopidine (generic name)

It helps to prevent blood clots
(tye KLOE pi deen)
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What is this medicine?

TICLOPIDINE (tye KLOE pi deen) helps to prevent blood clots. This medicine is used to prevent strokes in patients who have already had a stroke, or those who are at high risk of having a stroke. This medicine may also be used in combination with aspirin to prevent blood clots in patients who have had a coronary stent placed.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of the following conditions:
  • anemia
  • high cholesterol
  • history of bleeding disorder
  • kidney disease
  • liver disease
  • stomach ulcer
  • an unusual or allergic reaction to ticlopidine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take with food or just after eating to reduce stomach upset. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • agents that dissolve blood clots
  • antacids
  • antipyrine
  • aspirin and aspirin-like drugs
  • blood thinners such as warfarin
  • cimetidine
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • phenytoin
  • propranolol
  • theophylline

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Side effects to this medicine occur most frequently during the first 3 months of therapy. To make sure you do not develop any problems, you will need to have blood tests before you start this medicine and then every 2 weeks for the first 3 months.

This medicine can cause serious blood problems. This can mean risk of infection or bleeding. Avoid activities that increase your risk of bleeding. Tell your doctor or health care professional at once if have any unusual bleeding or bruise easily or an infection that will not get better.

If you are going to have surgery or dental work, tell your doctor or health care professional that you are taking this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • black, tarry stools
  • blood in urine
  • blood in vomit
  • difficulty breathing or wheezing
  • fever
  • joint pain or swelling
  • nosebleed
  • pain or difficulty passing urine
  • paleness
  • ringing in the ears
  • stomach pain
  • sudden weakness
  • unusual bleeding or bruising
  • yellowing of skin or eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • decreased appetite
  • diarrhea
  • headache
  • nausea, vomiting

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: September 03, 2009
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