phendimetrazine (generic name)
Plegine (brand name)
- Auto Immune Conditions
- Bladder & Kidney Health
- Brain & Nervous System
- Care Transitions
- Dental Health
- Emotional Health
- Eye Health
- Falls Prevention
- Financial Planning
- General Safety
- Health Care Basics
- Healthy Living
- Hearing Loss
- Heart Health
- High Blood Pressure
- Life Transitions
- Lung Health
- Men's Health
- Nutrition & Weight Management
- Pain Management
- Preventive Health
- Sexual Health
- Stomach & Digestive Health
- Stress & Anxiety
- Women's Health
What is this medicine?PHENDIMETRAZINE (fen dye MET ra zeen) decreases your appetite. It is used with a reduced calorie diet and exercise to help you lose weight.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- agitation or nervousness
- heart disease
- high blood pressure
- history of substance abuse
- kidney disease
- lung disease called Primary Pulmonary Hypertension (PPH)
- taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
- thyroid disease
- an unusual or allergic reaction to phendimetrazine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine 30 to 60 minutes before breakfast. Swallow whole. Do not open or chew the capsules. Do not take your medicine more often than directed. Do not suddenly stop taking your medicine because you may develop a severe reaction. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
- medicines for colds or breathing difficulties like pseudoephedrine or phenylephrine
- stimulants like dexmethylphenidate, methylphenidate or modafinil
This medicine may also interact with the following medications:
- medicines for diabetes
- medicines for high blood pressure
What should I watch for while using this medicine?Notify your physician immediately if you become short of breath while doing your normal activities.
Do not take this medicine within 6 hours of bedtime. It can keep you from getting to sleep. Avoid drinks that contain caffeine and try to stick to a regular bedtime every night.
This medicine was intended to be used in addition to a healthy diet and exercise. The best results are achieved this way. This medicine is only indicated for short-term use. Eventually your weight loss may level out. At that point, the drug will only help you maintain your new weight. Do not increase or in any way change your dose without consulting your doctor.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.