pentosan polysulfate sodium (generic name)

It is used to treat the bladder pain or discomfort caused by interstitial cystitis
(PEN toe san)
Table of Contents
powered by healthline

Average Ratings

What is this medicine?

PENTOSAN (PEN toe san) is used to treat the bladder pain or discomfort caused by interstitial cystitis. This is a condition that causes inflammation of parts of the kidney.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • kidney or liver disease
  • an unusual or allergic reaction to pentosan, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after food. Do not take with food. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • agents that prevent or dissolve blood clots like heparin or warfarin
  • aspirin, especially in higher doses
  • mifepristone

This medicine may also interact with the following medications:

  • clopidogrel
  • dipyridamole
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • ticlopidine

What should I watch for while using this medicine?

This medicine is a very weak blood thinner. Watch for any signs of blood in your urine or stools or for any unusual bruising or bleeding. This risk may be increased if you take any other medicines that may thin the blood (see drug interactions). You may wish to check with your health care professional prior to taking any non-prescription products containing aspirin. Read package labels carefully.

Tell your doctor or health care professional that you are taking this medicine if you are going to have a medical procedure or surgery.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • abdominal pain
  • blood in your urine or stools
  • bruising
  • coughing up blood
  • diarrhea
  • nosebleeds
  • rash
  • unusual bleeding

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • hair loss
  • headache
  • nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: May 06, 2010
Licensed from
Top of page
General Drug Tools
General Drug Tools view all tools
Tools for
Healthy Living
Tools for Healthy Living view all tools
Search Tools
Search Tools view all tools
Insurance Plan Tools
Insurance Plan Tools view all tools

What is a reference number?

When you register on this site, you are assigned a reference number. This number contains your profile information and helps UnitedHealthcare identify you when you come back to the site.

If you searched for a plan on this site in a previous session, you might already have a reference number. This number will contain any information you saved about plans and prescription drugs. To use that reference number, click on the "Change or view saved information" link below.

You can retrieve information from previous visits to this site, such as saved drug lists and Plan Selector information.