oxymorphone (generic name)

Opana (brand name)

It is used to treat moderate to severe pain
(ox i MOR feen)
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What is this medicine?

OXYMORPHINE (ox i MOR feen) is a pain reliever. It is used to treat moderate to severe pain. It is also used for pain or sleep before or during surgery or child birth. This medicine is used to treat anxiety in patients with breathing problems due to heart dysfunction.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • brain tumor
  • drug abuse or addiction
  • head injury
  • if you frequently drink alcohol-containing drinks
  • intestinal disease
  • kidney disease
  • kyphoscoliosis
  • liver disease
  • lung disease, asthma, or breathing problems
  • seizures
  • an unusual or allergic reaction to oxymorphone, codeine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a muscle or under the skin. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol or any product that contains alcohol

This medicine may also interact with the following medications:

  • antihistamines for allergy, cough and cold
  • atropine
  • benzodiazepines
  • certain medicines for bladder problems like oxybutynin, tolterodine
  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
  • certain medicines for stomach problems like dicyclomine, hyoscyamine
  • certain medicines for travel sickness like scopolamine
  • ipratropium
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • muscle relaxants
  • naltrexone
  • narcotic medicines (opiates) for pain
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

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Last Updated: August 23, 2012
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