omeprazole-sodium bicarbonate (generic name)

It prevents the production of acid in the stomach
(oh ME pray zol; SOE dee um bye KAR bon ate)
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What is this medicine?

OMEPRAZOLE; SODIUM BICARBONATE (oh ME pray zol; SOE dee um bye KAR bon ate) prevents the production of acid in the stomach. It is used to treat gastroesophageal reflux disease (GERD), ulcers, and inflammation of the esophagus.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • Bartter's syndrome
  • kidney disease
  • history of low levels of calcium, magnesium, or potassium in the blood
  • low salt diet
  • metabolic alkalosis
  • an unusual reaction to omeprazole, sodium bicarbonate, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Do not take with other drinks or foods. Follow the directions on the prescription label. Do not cut, crush or chew the capsules. Take this medicine on an empty stomach, at least 1 hour before a meal. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • atazanavir
  • clopidogrel
  • nelfinavir

This medicine may also interact with the following medications:

  • antibiotics like ampicillin, clarithromycin, tetracycline
  • antifungals like itraconazole, ketoconazole, and voriconazole
  • antivirals like delavirdine, efavirenz, indinavir, saquinavir
  • certain medicines that treat or prevent blood clots like warfarin
  • cyclosporine
  • dasatinib
  • digoxin
  • disulfiram
  • diuretics
  • iron supplements
  • medicines for anxiety, panic, and sleep like diazepam
  • medicines for seizures like carbamazepine, phenobarbital, phenytoin
  • other medicines for stomach acid
  • tacrolimus
  • tolmetin
  • vitamin B12

What should I watch for while using this medicine?

Visit your doctor for regular check ups. Tell your doctor if your symptoms do not get better or if they get worse.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

You may need blood work done while you are taking this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • bone, muscle or joint pain
  • breathing problems
  • chest pain
  • dark urine
  • diarrhea
  • dizziness
  • fast, irregular heartbeat
  • feeling faint or lightheaded, falls
  • fever or sore throat
  • high blood pressure
  • palpitations
  • muscle spasms
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • seizures
  • stomach pain
  • swelling of the ankles, legs
  • tremors
  • trouble passing urine or change in the amount of urine
  • unusual bleeding, bruising
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • dry mouth
  • headache
  • loose stools
  • nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: September 24, 2012
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