nateglinide (generic name)

It helps to control blood sugar
(nuh TAY gli nide)
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What is this medicine?

NATEGLINIDE (nuh TAY gli nide) helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetic ketoacidosis
  • kidney disease
  • liver disease
  • an unusual or allergic reaction to nateglinide, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. The dose should be taken no earlier than 30 minutes before every meal. If an extra meal is added, take a tablet before that meal. If a meal is skipped, skip the dose for that meal. Do not take more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose before a meal, skip that dose. If it is almost time for your next dose, take only that dose with the next scheduled meal as directed. Do not take double or extra doses.

What may interact with this medicine?

Many medications may cause an increase or decrease in blood sugar, these include:
  • alcohol containing beverages
  • aspirin and aspirin-like drugs
  • chloramphenicol
  • chromium
  • diuretics
  • female hormones, like estrogens or progestins and birth control pills
  • heart medicines
  • isoniazid
  • male hormones or anabolic steroids
  • medicines for weight loss
  • medicines for allergies, asthma, cold, or cough
  • medicines for mental problems
  • medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
  • niacin
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • other medicines for diabetes including tolbutamide
  • pentamidine
  • phenytoin
  • probenecid
  • quinolone antibiotics like ciprofloxacin, levofloxacin, ofloxacin
  • some herbal dietary supplements
  • steroid medicines like prednisone or cortisone
  • thyroid medicine

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

If you have low blood sugar, eat or drink something that has sugar. Make sure others know to get medical help quickly if you have serious symptoms of low blood sugar, like if you become unconscious or have a seizure.

If you need surgery, tell your doctor or health care professional that you are taking this medicine.

Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • dizziness
  • fast heart rate
  • low blood sugar (ask your doctor or healthcare professional for a list of these symptoms)
  • skin rash or itchy skin
  • sweating
  • tremor

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain
  • diarrhea
  • infection
  • joint pain
  • nausea/vomiting
  • upset stomach

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: July 10, 2009
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