methylene blue (generic name)

It is used to treat methemoglobinemia
(METH uh leen bloo)
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What is this medicine?

METHYLENE BLUE (METH uh leen bloo) is used to treat methemoglobinemia. This is a condition in which the blood loses its ability to carry oxygen through the body.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • cyanide poisoning
  • glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • kidney disease
  • an unusual or allergic reaction to methylene blue, phenothiazines, thiazide diuretics, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • bupropion
  • certain medicines for depression or anxiety
  • clomipramine
  • doxepin
  • duloxetine
  • fluoxetine
  • MAOIs like Marplan, Nardil, and Parnate
  • milnacipran
  • mirtazapine
  • rasagiline
  • selegiline
  • St. John's wort
  • trazodone
  • tryptophan

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • chest pain
  • confusion
  • dizziness
  • headache
  • increased sweating
  • stomach pain

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • blue-green coloration of urine and stools
  • nausea, vomiting
  • skin discoloration

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: November 19, 2012
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