METHADONE (METH a done) is a pain reliever. It is used to treat severe pain. The medicine is also used to prevent withdrawal symptoms in people addicted to other drugs.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
adrenal gland problem (Addison's disease)
drug abuse or addiction
fast or irregular heartbeat
frequently drink alcohol-containing drinks
kidney disease or problems going to the bathroom
low blood pressure
lung disease, asthma, COPD, or sleep apnea
an unusual or allergic reaction to methadone, other opioid analgesics, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
How should I use this medicine?
This medicine is for injection under the skin, into a muscle, or into a vein. It is usually given by a health care professional in a hospital or clinic setting.
If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
antibiotics like chloroquine, clarithromycin, erythromycin, grepafloxacin, pentamidine, sparfloxacin, troleandomycin
medicines for irregular heart beat like amiodarone, bretylium, disopyramide, dofetilide, procainamide, quinidine, sotalol
This medicine may also interact with the following medications:
antibiotics like gatifloxacin, gemifloxacin, levofloxacin, mefloquine, moxifloxacin, ofloxacin, telithromycin
antihistamines for allergy, cough and cold
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for blood pressure
medicines for depression, anxiety, or psychotic disturbances
medicines for irregular heart beat like flecainide, propafenone
medicines for nausea or vomiting like dolasetron, ondansetron, palonosetron
medicines for seizures like carbamazepine, phenobarbital, phenytoin
medicines for sleep
medicines for sleep during surgery
medicines to numb the skin
narcotic medicines (opiates) for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
some medcines for cancer like dasatinib, lapatinib, sunitinib
some medicines for HIV like delavirdine, didanosine, efavirenz, nevirapine