METHADONE (METH a done) is a pain reliever. It is used to treat severe pain. The medicine is also used to prevent withdrawal symptoms in people addicted to other drugs.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
adrenal gland problem (Addison's disease)
drug abuse or addiction
fast or irregular heartbeat
frequently drink alcohol-containing drinks
kidney disease or problems going to the bathroom
low blood pressure
lung disease, asthma, COPD, or sleep apnea
an unusual or allergic reaction to methadone, other opioid analgesics, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
How should I use this medicine?
Take this medicine by mouth with a drink of water. If the medicine upsets your stomach, take it with food or milk. Follow the directions on the prescription label. Do not take more medicine than you are told to take.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
antibiotics like chloroquine, clarithromycin, erythromycin, grepafloxacin, pentamidine, sparfloxacin, troleandomycin
medicines for irregular heart beat like amiodarone, bretylium, disopyramide, dofetilide, procainamide, quinidine, sotalol
This medicine may also interact with the following medications:
antibiotics like gatifloxacin, gemifloxacin, levofloxacin, mefloquine, moxifloxacin, ofloxacin, telithromycin
antihistamines for allergy, cough and cold
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for blood pressure
medicines for depression, anxiety, or psychotic disturbances
medicines for irregular heart beat like flecainide, propafenone
medicines for nausea or vomiting like dolasetron, ondansetron, palonosetron
medicines for seizures like carbamazepine, phenobarbital, phenytoin
medicines for sleep
medicines for sleep during surgery
medicines to numb the skin
narcotic medicines (opiates) for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
some medicines for cancer like dasatinib, lapatinib, sunitinib
some medicines for HIV like delavirdine, didanosine, efavirenz, nevirapine