metformin-repaglinide (generic name)

It is used to treat type 2 diabetes
(met FOR min; re PAG lin ide)
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What is this medicine?

METFORMIN; REPAGLINIDE (met FOR min; re PAG lin ide) is used to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body to use insulin better.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • anemia
  • frequently drink alcohol-containing beverages
  • become easily dehydrated
  • heart attack
  • heart failure that is treated with medications
  • kidney disease
  • liver disease
  • polycystic ovary syndrome
  • serious infection or injury
  • vomiting
  • an unusual or allergic reaction to metformin, repaglinide, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Swallow it with a drink of water. Follow the directions on the prescription label. Take this medicine before meals. It should be taken no earlier than 30 minutes before meals. If a meal is skipped, skip the dose for that meal. Do not take more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Elderly patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose before a meal, skip that dose. If it is almost time for your next dose, take only that dose with the next scheduled meal as directed. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • certain contrast medicines given before X-rays, CT scans, MRI, or other procedures
  • dofetilide
  • gatifloxacin
  • gemfibrozil

This medicine may also interact with the following medications:

  • cimetidine
  • clarithromycin
  • amiloride
  • digoxin
  • diuretics
  • female hormones, like estrogens or progestins and birth control pills
  • isoniazid
  • isophane insulin (NPH)
  • medicines for blood pressure, heart disease, irregular heart beat
  • medicines for fungal or yeast infections such as itraconazole, ketoconazole, miconazole
  • morphine
  • nicotinic acid
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • phenytoin
  • procainamide
  • quinidine
  • quinine
  • ranitidine
  • rifampin
  • simvastatin
  • steroid medicines like prednisone or cortisone
  • stimulant medicines for attention disorders, weight loss, or to stay awake
  • thyroid medicines
  • trimethoprim
  • vancomycin

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

If you have low blood sugar, eat or drink something that has sugar. Make sure others know to get medical help quickly if you have serious symptoms of low blood sugar, like if you become unconscious or have a seizure.

If you need surgery or if you will need a procedure with contrast drugs, tell your doctor or health care professional that you are taking this medicine.

Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.

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Last Updated: July 08, 2009
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