loteprednol-tobramycin ophthalmic (generic name)

Zylet (brand name)

It is used to treat bacterial eye infections
(loe te PRED nol; toe bra MYE sin)
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What is this medicine?

LOTEPREDNOL; TOBRAMYCIN (loe te PRED nol; toe bra MYE sin) contains a steroid and an aminoglycoside antibiotic. It is used to treat bacterial eye infections. It will also decrease swelling, redness, and itching.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • any active infection of the eye
  • cataracts or glaucoma
  • wear contact lenses
  • an unusual or allergic reaction to loteprednol, tobramycin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. Shake well before using. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper, or tube, to your eye, fingertips, or other surface. Squeeze the prescribed number of drops into the pouch. Do not blink. Close the eye gently to spread the drops. Keep the eyes closed and apply gentle pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if your condition is better.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Interactions are not expected. Do not use any other eye products without telling your doctor or health care professional.

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Tell your doctor or health care professional if you are exposed to anyone with measles or chickenpox or if you develop sores or blisters that do not heal properly.

If you wear contact lenses, ask your doctor or health care professional when you can use your lenses again.

A burning or stinging reaction that does not go away may mean you are allergic to this product. Stop using and call your doctor or health care professional.

This medicine can make certain eye conditions worse. Only use it for conditions for which your doctor or health care professional has prescribed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • burning, stinging or swelling of the eyelids
  • eye pain, decreased or blurred vision (that will not go away)
  • infection
  • watery eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • mild burning, redness, or stinging in the eye
  • eye irritation
  • temporary watering or blurring of vision

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Last Updated: June 23, 2009
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