loratadine-pseudoephedrine (generic name)

Clear-Atadine-D (brand name)

This medicine is used to treat the symptoms of allergies
(lor AT a deen; soo doe e FED rin)
Table of Contents
powered by healthline

Average Ratings

What is this medicine?

LORATADINE; PSEUDOEPHEDRINE (lor AT a deen; soo doe e FED rin) is a combination of an antihistamine and a decongestant. This medicine is used to treat the symptoms of allergies. It reduces congestion, sneezing, runny nose, and itching.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • difficulty urinating
  • heart disease
  • high blood pressure
  • kidney disease
  • liver disease
  • thyroid disease
  • an unusual or allergic reaction to loratadine, pseudoephedrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the label. You can take it with or without food. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be used in children as young as 12 years for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • bromocriptine
  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for allergies, colds, breathing difficulties
  • procarbazine
  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • digoxin
  • efavirenz
  • linezolid
  • medicines for depression like amitriptyline, nortriptyline
  • medicines for heart disease or blood pressure like atenolol, clonidine, doxazosin, mecamylamine, methyldopa, reserpine
  • St. John's wort
  • theophylline
  • tizanidine
  • yohimbine

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better, if they get worse or if you have a high fever. If you have high blood pressure, check your blood pressure regularly. Ask your health care professional what your blood pressure should be, and when you should contact him or her.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash or hives, swelling of the face, lips, or tongue
  • breathing trouble
  • difficulty urinating
  • difficulty sleeping
  • dizzy, faint
  • fast, irregular heartbeat
  • high blood pressure
  • nervousness, agitation
  • tremor, muscle contractions
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • cough
  • dry mouth
  • headache
  • loss of appetite
  • nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: June 22, 2009
Licensed from
Top of page
General Drug Tools
General Drug Tools view all tools
Tools for
Healthy Living
Tools for Healthy Living view all tools
Search Tools
Search Tools view all tools
Insurance Plan Tools
Insurance Plan Tools view all tools

What is a reference number?

When you register on this site, you are assigned a reference number. This number contains your profile information and helps UnitedHealthcare identify you when you come back to the site.

If you searched for a plan on this site in a previous session, you might already have a reference number. This number will contain any information you saved about plans and prescription drugs. To use that reference number, click on the "Change or view saved information" link below.

You can retrieve information from previous visits to this site, such as saved drug lists and Plan Selector information.