indomethacin (generic name)

Indocin (brand name)

It is used to reduce swelling and to treat pain
(in doe METH a sin)
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What is this medicine?

INDOMETHACIN (in doe METH a sin) is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. It may be used for painful joint and muscular problems such as arthritis, tendinitis, bursitis, and gout.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • asthma, especially aspirin sensitive asthma
  • cigarette smoker
  • coronary artery bypass graft (CABG) surgery within the past 2 weeks
  • depression
  • drink more than 3 alcohol-containing drinks a day
  • heart disease or circulation problems like heart failure or leg edema (fluid retention)
  • high blood pressure
  • kidney disease
  • liver disease
  • Parkinson's disease
  • seizures
  • stomach bleeding or ulcers
  • an unusual or allergic reaction to indomethacin, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with food and with a full glass of water. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon or container to measure the medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take your medicine more often than directed. Long-term, continuous use may increase the risk of heart attack or stroke.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 15 years for selected conditions, precautions do apply.

Elderly patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • cidofovir
  • diflunisal
  • ketorolac
  • methotrexate
  • pemetrexed
  • triamterene

This medicine may also interact with the following medications:

  • alcohol
  • antacids
  • aspirin and aspirin-like medicines
  • cyclosporine
  • digoxin
  • diuretics
  • lithium
  • medicines for diabetes
  • medicines for high blood pressure
  • medicines that affect platelets
  • medicines that treat or prevent blood clots like warfarin
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • probenecid
  • steroid medicines like prednisone or cortisone

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Last Updated: May 05, 2009
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